Faculty

Home> Faculty> Preventive Veterinary Medicine

Preventive Veterinary Medicine

Cheng He, DVM, PhD

Professor of Preventive Veterinary Medicine
Director, China-ASEAN Innovative Academy for Major Animal Disease Control
Coordinator of PAK-China Agricultural Technology, Innovation & Extension Center

chenghe@cau.edu.cn,hehonest@aliyun.com

010-62733613

Education

  • 2004/8-2005/7, MD Diploma, Manchester University, Bilingual Education, 

  • 1999/9 - 2001/6, PhD in Animal physiology, China Agricultural University

  • 1996/9 - 1998/7, MS in Veterinary Pathology, China Agricultural University

  • 1985/9 - 1990/7, DVM, Beijing Agricultural University


Training and Professional Experience

  • 2008/12-present, Professor China Agricultural University, College of Veterinary Medicine.

  • 2021/11-present, Director, China-ASEAN Innovative Academy for Major Animal Disease Control.

  • 2018/5-present, Coordinator of PAK-China Agricultural Technology, Innovation & Extension Center.

  • 2017/6-2023/12 Distinguished professor(contract job), Foshan university, College of Life Sciences and Engineering.

  • 2019/8-2020/12, project leader of Consortium for Veterinary Medical Product Manufacturers along Lancang-Mekong River.

  • 2016/1-2020/12 Distinguished Professor, Shandong Binzhou Animal Science and Veterinary Medicine Academy, awarded by Shandong Government.

  • 2013/1-2014/2 Postdoctoral researcher, Morehouse School of Medicine, Atlanta, USA, Supervisor: Francis Omino Eko, Professor.

  • 2009/10-2011/12, Scientific consultant, Ministry of Education, Ministry of Science and Technology and Guangdong Province, China.

  • 2001/9 - 2008/11, Associate professor, China Agricultural University, College of Veterinary Medicine.

  • 2005/1 - 2005/7, Moredun Research Institute, UK, Visiting scholar, Supervisor: David Longbottom.


Research Interests

Dr. He has contributed to zoonotic infection originated from animal industry and human health as well for 20 years. Recently, new hypothesis of feed-borne Bacillus cereus associated with gastric ulceration and diarrhea is the second research interests.


  1. Chlamydia infection and immunity. Dr. He is dedicating to illustrate the mechanism of diverse hosts of Chlamydia psittaci compared to single human host targeted by Chlamydia trachomatis and Chlamydia pneumonia.To uncode Chlamydia-binded receptors of host cells, Dr. He team wish to identify the biomarkers for combating Chlamydial transmission from animals to human beings.

  2. Mycotoxin inhibition and detoxification. Feed-borne Bacillus spp. are re-emerging pathogens and threating to food safety post antibiotic reduction program. Gastric ulceration, diarrhea and immune suppression are hampering sustainable animal industry due to no maximal tolerance limits(MTL).Based on investigation, Dr. He wish to establish MTL standard of pathogenic Bacillus spp.and develop highly efficient detoxification for animal industry.


Awards

  • Cheng He (1/22). Comprehensive measures against pigeons' diseases. Ministry of Agriculture, China. Harvest Award (2nd class prize). 2010.

  • Cheng He (1/25). Strategic controls for Chlamydiosis and applied technology for animal industry. Ministry of Education, China. Scientific and Technologic Progress Award (1st class prize). 2008.


Teaching

  • 2006-now, Undergraduate course "Experimental Animals"

  • 2006-2017, Undergraduate course "Diagnostic practice for poultry disease"

  • 2018-now, Undergraduate course "Animal welfare and protection"

  • 2015-now, Graduate level course "Advanced laboratory animal sciences"


Reviewer for

  • Veterinary Microbiology

  • Frontier in Microbiology

  • Plos One

  • Toxins

  • Microbial Pathogenesis

  • Environmental Science and Pollution Research


Service

  • 2018-Now, Editorial Board Member of Frontiers in Veterinary Science

  • 2020-Now, Editorial Board Member of Animals

  • 2016-Now, Editorial Board Member of Pakistan Veterinary Science

  • 2020-Now,Editorial Board Member of Tropic Biology Journal


Selected Publications

2022

  • Li XH, Zuo ZH, Wang YH, Hegemann JH, He C. Polymorphic membrane protein 17G of Chlamydia psittaci mediated the invasion of bacteria to host cells by binding EGFR. Front. Immunol. 2022, 12:818487.

  • Li Q, Chen Sy, Yan ZQ, Fang HX, Wang ZX, He C. A novel intranasal vaccine with PmpG+MOMP induces robust protections both in respiratory tract and genital system posting Chlamydia psittaci infection. Front Vet Sci. 2022. 9: 855447. DOI: 10.3389/fvets.2022.855447.

  • Md.Aminul Islam, Tuhin Das, Md. Arifur Rahman, Foysal Hossen, Mahin Reza, Sumit Kumar Barral, Md. Atiqul Haque, Cheng He, Firoz Ahmed. A Review on Measures to Rejuvenate Immune System: Natural Mode of Protection Against Coronavirus Infection. Front. Immunol, 2022, 13:837290. DOI: 10.3389/fimmu.2022.837290.

2021

  • Qiang Li, Xiaohui Li, Hongkun Quan, Yihui Wang, Guanggang Qu, Zhiqiang Shen, Cheng He. IL-10 -/- Enhances DCs Immunity Against Chlamydia psittaci Infection via OX40L/NLRP3 and IDO/Treg Pathways. Front Immunol. 2021,12:645653.

  • Haque MA, Wang F,Chen Y, Firoz A, Siddique N, He C. Bacillus spp. contamination: a novel risk originated from animal feed to human food chains in South-Eastern Bangladesh. Front. Microbiol. 2021, 12: 783103.

  • Wang YH, Quan HQ, Li XH, Li Q, Haque MA, Shi Q, Fu Q, He C. Contamination with Fumonisin B and Deoxynivalenol is a threat to egg safety and contributes to gizzard ulcerations of newborn chickens. Frontiers in Microbiology. 2021, 12:676671.

  • Zuo Z, Zou Y, Li Q, Guo Y, Zhang T, Wu J, He C, Eko FO.Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge.Sci Rep. 2021,11 (1):10389.

  • Fang Huanxin, Quan Hongkun, Zhang Yuhang, Li Qiang, Wang Yihui, Yuan Sheng,Huang Shujian, He Cheng. Co-infection of Escherichia coli, Enterococcus faecalis and Chlamydia psittaci contributes to salpingitis of laying hens and breeder ducks. Pathogens. 2021.6 (10):755.

  • Cui L, Qu G, Chen Y, Wu Y, Wang C, Cheng H, Chen J. Polymorphic membrane protein 20G: A promising diagnostic biomarker for specific detection of Chlamydia psittaci infection. Microb Pathog. 2021,155:104882.

2020

  • Xiaohui Li, Qiang Li, Yihui Wang, Zhenhai Han, Guanggang Qu, Zhiqiang Shen, Shujian Huang, Cheng He. Gastric Ulceration and Immune Suppression in Weaned Piglets Associated with Feed-Borne Bacillus cereus and Aspergillus fumigatus. Toxins, 2020, 12 (11):203.

  • Chu J, Li XH, Qu GG, Wang YH, Li Q, Guo YX, Hou L, Liu J, Eko FO and He C. Chlamydia psittaci PmpD-N Exacerbated Chicken Macrophage Function by Triggering Th2 Polarization and the TLR2/MyD88/NF-κB Signaling Pathway. International Journal of Molecular Sciences. 2020, 21, 2003.

  • Zonghui Zuo, Qiang Li, Yongxia Guo, Xiaohui Li,Shujian Huang, Johannes H. Hegemann, Cheng He. Feed-borne Bacillus cereus exacerbates respiratory distress in birds infected with Chlamydia psittaci by inducing hemorrhagic pneumonia. Avian Pathology, 2020 Jan 17:1-31. doi: 10.1080/03079457.2020.1716940.

  • Md Atiqul Haque, Yihui Wang, Zhiqiang Shen, Muhammad Kashif Saleemi, Xiaohui Li, Cheng He. Mycotoxin Contamination and Control Strategy in Human, Domestic Animal and Poultry: A Review. Microbial Pathogenesis. 2020. 142. 104095.

  • Jun Chu, Yongxia Guo, Guanlong Xu, Qiang Zhang, Zonghui Zuo, Qiang Li, Yihui Wang, Cheng He. Chlamydia psittaci triggers the invasion of H9N2 avian influenza virus by impairing the functions of chicken macrophages. Animals 2020, 10, 2-18.

2019

  • Qiang Zhang, Zuo Zonghui, Yongxia Guo, TianYuan Zhang, Zhenhai Han, Shujian Huang, Musafiri Karama, Muhammad Kashif Saleemi, Ahrar Khan, Cheng He. Contaminated feed-borne Bacillus cereus aggravates respiratory distress post avian influenza virus H9N2 infection by inducing pneumonia. Scientific Reports, 2019, 9:7231.

  • Zhang TY, Huo Z, Ma JY, He C, Zhong GM. The plasmid-encoded pGP3 promotes Chlamydia evasion of acidic barriers in both stomach and vagina. Infection and Immunity. Infect. Immun. 2019, 87(5). e00844-18. doi:10.1128/IAI.00844-18.

  • Mohsin M, Van Boeckel TP, Saleemi MK, Umair M, Naseem MN, He C, Khan A, Laxminarayan R. Excessive use of medically important antimicrobials in food animals in Pakistan: a five-year surveillance survey. Glob Health Action. 2019; 12(sup1):1697541.

  • Saleemi MK, Ashraf K, Gul ST, Naseem MN, Sajid MS, Mohsin M, He C, Zubair M, Khan A. Toxicopathological effects of feeding aflatoxins B1 in broilers and its ameliosration with indigenous mycotoxin binder. Ecotoxicol Environ Saf. 2020,15;187:109712. doi: 10.1016/j.ecoenv.2019