Geng Meng, DVM, PhD

Education

• 09/2005-07/2010, PhD in Biochemistry and molecular biology, Peking University

• 09/2000-07/2005, DVM, China Agricultural University

Training and Professional Experience

• 2017-now, Associate Professor, China Agricultural University College of Veterinary Medicine

• 2016-2017, Scientific Consultant, BBI Solution

• 2010-2016, Postdoctoral Fellow, School of Life Sciences, Purdue University

Research Interests

Dr. Meng's current research interest focuses on the structural virology in order to understand the assembly of RNA viruses and giant DNA viruses (ASFV). The main purpose of the study is to prevent the emerging pathogenic viruses which is harmful to the environment, animal and human health.

Teaching

• 2021-now, Undergraduate course "Structural Virology in Veterinary Medicine"
  

• 2018-2020, Undergraduate course "Veterinary Biometrics"
  

Reviewer for

• Frontier in Microbiology

• Transboundary and Emerging Diseases

• Acta Physiologica

• Database (Oxford)

Selected Publications

Corresponding author:

• Qu Z., Kang H., Cui C., Meng K., Zhang X., Qu L., Zhang Y.*, Meng G.*. Purification Induced Damage to the Calicivirus Particles at Near-atomic Resolution. J Gen Virol. 2022. (Accept)

• Zhu W, Meng K, Zhang Y, Bu Z, Zhao D*, Meng G*. Lateral Flow Assay for the Detection of African Swine Fever Virus Antibodies Using Gold Nanoparticle-Labeled Acid-Treated p72. Front Chem. 2022 Jan 3;9:804981.

• Wu H, Xing N, Meng K, Fu B, Xue W, Dong P, Tang W, Xiao Y, Liu G, Luo H, Zhu W, Lin X*, Meng G*, Zhu Z*. Nucleocapsid mutations R203K/G204R increase the infectivity, fitness, and virulence of SARS-CoV-2. Cell Host Microbe. 2021 Dec 8;29(12):1788-1801.e6.

• Zhu Z*, Meng K, Liu G, Meng G*. A database resource and online analysis tools for coronaviruses on a historical and global scale. Database (Oxford). 2021 Aug 5;2020:baaa070.

• Fu J, Zhang Y, Cai G, Meng G*, Shi S*. Rapid and sensitive RPA-Cas12a-fluorescence assay for point-of-care detection of African swine fever virus. PLoS One. 2021 Jul 19;16(7):e0254815.

• Zhu Z*, Liu G, Meng K, Yang L, Liu D, Meng G*. Rapid Spread of Mutant Alleles in Worldwide SARS-CoV-2 Strains Revealed by Genome-Wide Single Nucleotide Polymorphism and Variation Analysis. Genome Biol Evol. 2021 Feb 3;13(2):evab015.

• Zhu Z*; Meng K; Meng G*. Genomic recombination events may reveal the evolution of coronavirus and the origin of SARS-CoV-2. Scientific Reports, 2020, 10(1): 0-21617.

• Zhang L, Li X, Ma L, Zhang B, Meng G*, Xia C*. A Newly Recognized Pairing Mechanism of the α- and β-Chains of the Chicken Peptide-MHC Class II Complex. J Immunol. 2020 Mar 15;204(6):1630-1640.

• Zhu Z*, Meng G*. ASFVdb: an integrative resource for genomic and proteomic analyses of African swine fever virus. Database (Oxford). 2020 Jan 1;2020:baaa023.

• Chen C., Yu X., Han D., Ai J., Ke Y., Wang Z.*; Meng G.*. Non-CTAB synthesized gold nanorods-based immunochromatographic assay for dual color and on-site detection of aflatoxins and zearalenones in maize. Food Control, 2020, 118: 0-107418.

• Zhu Z*, Wang Y, Zhou X, Yang L, Meng G*, Zhang Z. SWAV: a web-based visualization browser for sliding window analysis. Sci Rep. 2020 Jan 10;10(1):149.

First author:

• Xiao W#, Meng G#, Zhao Y, Yuan H, Li T, Peng Y, Zhao Y, Luo M, Zhao W, Li Z, Zheng X. Human secreted stabilin-1-interacting chitinase-like protein aggravates the inflammation associated with rheumatoid arthritis and is a potential macrophage inflammatory regulator in rodents. Arthritis Rheumatol. 2014 May;66(5):1141-52.

• Meng G#, An X#, Ye S, Liu Y, Zhu W, Zhang R*, Zheng X*. The crystal structure of LidA, a translocated substrate of the Legionella pneumophila type IV secretion system. Protein Cell. 2013 Dec;4(12):897-900.

• Meng G, Zhang X, Plevka P, Yu Q, Tijssen P, Rossmann MG*. The structure and host entry of an invertebrate parvovirus. J Virol. 2013 Dec;87(23):12523-30.

• Battisti AJ#, Meng G#, Winkler DC, McGinnes LW, Plevka P, Steven AC, Morrison TG, Rossmann MG*. Structure and assembly of a paramyxovirus matrix protein. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):13996-4000.

• Bai X#, Meng G#, Luo M, Zheng X*. Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules. J Biol Chem. 2012 Jun 22;287(26):22387-96.

• Meng G, Zhao Y, Bai X, Liu Y, Green TJ, Luo M, Zheng X*. Structure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity. J Biol Chem. 2010 Dec 17;285(51):39898-904.

Authorized Patents:

• Meng G., Zhang Y., Zhu W., Xiang Y., Liu Q., Meng K. African swine fever virus capsid protein p72 and its preparation method and application, CN112979765

• Meng G., Zhu W., Meng K., Tang Z. A chimeric antigen of bovine coronavirus and a colloidal gold immunochromatographic strip for detecting bovine coronavirus antibodies, CN110894217

• Meng G., Zhu W., Meng K., Tang Z. A chimeric antigen of bovine rotavirus and a colloidal gold immunochromatographic strip for detecting bovine rotavirus antibodies, CN110903403

• Meng G., Zhu W., Meng K. An antigen of Peste des petits ruminants virus and a colloidal gold immunochromatographic strip for detecting Peste des petits ruminants virus antibodies, CN110894215

• Meng G., Zhu W. Preparation method of ultra-uniform spherical gold nanoparticles with different diameter, CN111468741

• Meng G., Zhu W., Gu G. A chimeric antigen of porcine reproductive and respiratory syndrome virus and a colloidal gold immunochromatographic strip for detecting porcine reproductive and respiratory syndrome virus antibodies, CN110894243

• Meng G., Zhu W., Gu G. An antigen of porcine circovirus type 2 and a colloidal gold immunochromatographic strip for detecting porcine circovirus type 2 antibodies, CN110903356

• Meng G., Bu Z., Zhao D., Zhu W., Zhang Y., Liu W., Liu R. A colloidal gold immunochromatographic strip for detecting African swine fever virus antibodies, CN113721035