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Preventive Veterinary Medicine

Juan Pu, DVM, PhD

Professor of Preventive Veterinary Medicine
Director of the T & R Group of Veterinary Infectious Diseases and Microbiology

pujuan@cau.edu.cn

010-62733990

Education

  • 09/2005-06/2008, PhD in Preventive Veterinary Medicine, China Agricultural University, Beijing

  • 09/2003-06/2005, MS in Preventive Veterinary Medicine, China Agricultural University, Beijing

  • 09/1998-06/2003, DVM, China Agricultural University, Beijing


Research Interests

  • Animal influenza virus

Epidemiology and ecology of animal influenza virus by tracking the emergence and transmission of animal influenza virus in environment, animal, and human, focusing on the impact of influenza virus on domestic animals and its public health hazards, revealing the mechanism of virus pathogenicity and interspecies transmission, so as to explore the key risk factors of animal influenza virus transmission in the ecosystem, and to provide a theoretical basis for scientific prevention and control of zoonotic diseases such as animal influenza.


Training and Professional Experience

  • 01/2018-now, Professor, China Agricultural University, College of Veterinary Medicine

  • 11/2013-12/2014, Visiting Scholar, St Jude Children’s Research Hospital, USA

  • 02/2013-04/2013, Visiting Scholar, University of Nottingham, UK

  • 01/2012-12/2017, Associate Professor, China Agricultural University, College of Veterinary Medicine

  • 09/2008-12/2011, Assistant Professor, China Agricultural University, College of Veterinary Medicine


Awards and Honors

  • 2019, National Excellent Young Investigator, China

  • 2015, First prize of Beijing Young Teachers Teaching Basic Skills Competition, Beijing, China

  • 2013, New Century Excellent Talents in University, Ministry of Education, China

  • 2013, Beijing Youth Talents of Universities, Beijing, China


Teaching

  • 2016-now, Undergraduate course “Animal Husbandry Microbiology”

  • Participated, Undergraduate course "Experiment of Veterinary Infectious Diseases"

  • Participated, Undergraduate course "Veterinary Microbiology"

  • Participated, Postgraduate courses "Special Topics on Animal Infectious Diseases"

  • Participated, Postgraduate courses "Practice of Prevention and Control of Important Animal Diseases"


Reviewer for

  • Veterinary Microbiology

  • Emerging Microbes & Infections


Service

  • 2019-Now, Member of Avian Disease Branch of Chinese Association of Animal Science and Veterinary Medicine

  • 2019-Now, Executive Member of Beijing Society for Microbiology

  • 2021-Now, Executive Member of Chinese Society for Microbiology


Selected Publications

  • Wang C, Qu R, Zong Y, Qin C, Liu L, Gao X, Sun H, Sun Y, Chang KC, Zhang R, Liu J, Pu J*. Enhanced stability of M1 protein mediated by a phospho-resistant mutation promotes the replication of prevailing avian influenza virus in mammals. PLoS Pathog. 2022 Jul 6; 18(7): e1010645.

  • Pu J#, Yin Y#, Liu J, Wang X, Zhou Y, Wang Z, Sun Y, Sun H, Li F, Song J, Qu R, Gao W, Wang D, Wang Z, Yan S, Chen M, Zeng J, Jiang Z, Sun H, Zong Y, Wang C, Tong Q, Bi Y, Huang Y, Du X, Chang KC, Liu J*. Reassortment with dominant chicken H9N2 influenza virus contributed to the fifth H7N9 virus human epidemic. J Virol. 2021 Mar 17:JVI.01578-20.

  • Song J, Wang C, Gao W, Sun H, Jiang Z, Wang K, Ren X, Wang Z, Tong Q, Wang M, Sun H, Sun Y, Liu J, Pu J*. A D200N hemagglutinin substitution contributes to antigenic changes and increased replication of avian H9N2 influenza virus. Vet Microbiol. 2020 Jun;245:108669.

  • Gao W, Zu Z, Liu J, Song J, Wang X, Wang C, Liu L, Tong Q, Wang M, Sun H, Sun Y, Liu J, Chang KC, Pu J*. Prevailing I292V PB2 mutation in avian influenza H9N2 virus increases viral polymerase function and attenuates IFN-β induction in human cells. J Gen Virol. 2019 Sep;100(9):1273-1281.

  • Wang C, Wang Z, Ren X, Wang L, Li C, Sun Y, Wang M, Tong Q, Sun H, Pu J*. Infection of chicken H9N2 influenza viruses in different species of domestic ducks. Vet Microbiol. 2019 Jun;233:1-4.

  • Li C, Wang S, Bing G, Carter RA, Wang Z, Wang J, Wang C, Wang L, Wu G, Webster RG, Wang Y, Sun H, Sun Y, Liu J, Pu J*. Genetic evolution of influenza H9N2 viruses isolated from various hosts in China from 1994 to 2013. Emerg Microbes Infect. 2017 Nov 29;6(11):e106.

  • Pu J#, Sun H#, Qu Y, Wang C, Gao W, Zhu J, Sun Y, Bi Y, Huang Y, Chang KC, Cui J, Liu J*. M Gene Reassortment in H9N2 Influenza Virus Promotes Early Infection and Replication: Contribution to Rising Virus Prevalence in Chickens in China. J Virol. 2017 Mar 29;91(8):e02055-16.

  • Xu G#, Zhang X#, Gao W, Wang C, Wang J, Sun H, Sun Y, Guo L, Zhang R, Chang KC, Liu J, Pu J*. Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity. J Virol. 2016 Aug 26;90(18):8105-14.

  • Wei Y, Xu G, Zhang G, Wen C, Anwar F, Wang S, Lemmon G, Wang J, Carter R, Wang M, Sun H, Sun Y, Zhao J, Wu G, Webster RG, Liu J, Pu J*. Antigenic evolution of H9N2 chicken influenza viruses isolated in China during 2009-2013 and selection of a candidate vaccine strain with broad cross-reactivity. Vet Microbiol. 2016;182:1-7.

  • Pu J#, Wang S#, Yin Y#, Zhang G, Carter RA, Wang J, Xu G, Sun H, Wang M, Wen C, Wei Y, Wang D, Zhu B, Lemmon G, Jiao Y, Duan S, Wang Q, Du Q, Sun M, Bao J, Sun Y, Zhao J, Zhang H, Wu G, Liu J*, Webster RG*. Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):548-53.