Faculty

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Preventive Veterinary Medicine

Wenxue Wu, PhD

Professor of Preventive Veterinary Medicine

wuwenxue@cau.edu.cn

010-62733048

Education

  • 09/1997-07/2002, PhD in Preventive Veterinary Medicine, China Agricultural University

  • 09/1989-07/1994, DVM, Beijing Agricultural University


Training and Professional Experience

  • 2016-now, Professor, China Agricultural University College of Veterinary Medicine

  • 2013-2014, Visiting Scholar, Harvard Medicine College

  • 2005-2015, Associate Professor, China Agricultural University College of Veterinary Medicine


Research Interests

  • Pathogenic Mechanism

  • Immune Regulation Mechanism

  • Vaccines

  • Diagnostic Technology


Awards and Honors

  • 2009, New Century Excellent Talent, China


Service

  • 2017-Now, Editorial Board Member of Chinese Journal of Veterinary Medicine


Selected Publications

  • Li P, Zhang Y, Li X, Zhou W, Li X, Jiang F, Wu W*. Mycoplasma hyopneumoniae Mhp597 is a cytotoxicity, inflammation and immunosuppression associated nuclease[J]. Vet Microbiol, 2019,235:53-62.

  • Zhang Y K, Li X, Zhao H R, Jiang F, Wang Z H, Wu W X*. Antibodies Specific to Membrane Proteins Are Effective in Complement-Mediated Killing of Mycoplasma bovis[J]. Infect Immun, 2019,87(12).

  • Li X, Zhang Y K, Yin B, Liang J B, Jiang F, Wu W X*. Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by Mycoplasma hyopneumoniae[J]. Infect Immun, 2019,88(1).

  • Li P, Xu J, Rao H M, Li X, Zhang Y K, Jiang F, Wu W X*. Mechanism of Apoptosis Induction by Mycoplasmal Nuclease MGA_0676 in Chicken Embryo Fibroblasts[J]. Front Cell Infect Microbiol, 2018,8:105.

  • Zhou Y, Wu W*, Lindholt JS, Sukhova GK, Libby P, Yu X, Shi GP .Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms.Cardiovasc Res. 2015 Jul 1;107(1):98-107.

  • Zhang Y, Yu Z, Jiang F, Fu P, Shen J, Wu W*, Li J. Two DNA aptamers against avian influenza H9N2 virus prevent viral infection in cells. PLoS One. 2015 Mar 31;10(3):e0123060.

  • Jiahe Li, Jixiang Zhang, Ning Zhang, Yuewei Zhang, Wenxue Wu*, Jinxiang Li. Development of a replicative plasmid for gene expression in Mycoplasma bovis. Journal of Microbiological Methods, Jan. 2015 ( IF=2.096)

  • Jian Xu, Da Teng, Fei Jiang, Yuewei Zhang, Saeed A. El-Ashrom, Hui Wang, Zhenhong Sun, Jinyan He, Junjun Shen, Wenxue Wu*, Jinxiang Li. Mycoplasma gallisepticum MGA_0676 is a membrane-associated cytotoxic nuclease with a staphylococcal nuclease region essential for nuclear translocation and apoptosis induction in chicken cells, Appl Microbio Biotechnol. Feb. 2015

  • Wang J, Sjöberg S, Tang TT, Oörni K, Wu W, Liu C, Secco B, Tia V, Sukhova GK, Fernandes C, Lesner A, Kovanen PT, Libby P, Cheng X, Shi GP.Cathepsin G activity lowers plasma LDL and reduces atherosclerosis. Biochim Biophys Acta-Molecular Basis of Disease, Nov;1842(11):2174-83,2014

  • Fu P, Sun ZH, Yu ZQ, Zhang YW, Shen JJ, Zhang HY, Xu W, Jiang F, Chen HL, Wu WX*. Enzyme Linked Aptamer Assay (ELAA),based on a competition format for rapid and sensitive detection of antibodies to Mycoplasma bovis in serum, Analytical Chemistry, 86(3):1701-1709, 2014

  • Zhenhong Sun, Ping Fu, Kai Wei, Haiyan Zhang, Yuewei Zhang, Jian Xu, Fei Jiang, Xu Liu, Wei Xu, Wenxue Wu*. Identification of novel immunogenic proteins of Mycoplasma bovis and establishment of an indirect ELISA based on recombinant E1 beta subunit of the pyruvate dehydrogenase complex. PLoS One, 10;9(2):e88328. doi: 10.1371/ journal.pone.0088328. eCollection ,2014

  • Yue-Wei Zhang, Hai-Yu Yan, Ping Fu, Fei Jiang, Yao Zhang, Wen-Xue Wu*, Jin-Xiang Li*. Modified capillary electrophoresis based measurement of the binding between DNA aptamers and an unknown concentration target. Anal Bioanal Chem, http://dx. doi.org/10.1007/s00216-013-6968-0 ,2013