Chongshan Dai, PhD
Associate Professor of Basic Veterinary Medicine
09/2013-07/2017, PhD, Basic Veterinary Medicine, China Agricultural University
09/2010-07/2013, Master, Basic Veterinary Medicine, Northeast Agricultural University
09/2006-07/2010, Bachelor, and Plant Quarantine, Henan University of Science and Technology
Training and Professional Experience
2021-now, Associated Professor, China Agricultural University College of Veterinary Medicine
2017-2020, Postdoctoral Fellow, Department of Internal Medicine, University of Texas Southwestern Medicine Center
Cell Death and Metabolic Diseases
Molecular Toxicology of Antibacterial Drugs
Risk Assessment of Environmental Hazard Factor (e.g., Heavy Metals, Toxins, etc.)
Awards and Honors
2014, 2015, 2016, Postgraduate (PhD) National Scholarship, China (3 Times)
2014, Outstanding Paper Award of the Chinese Society of Environmental Mutagens
2021-now, Undergraduate Course "Animal Toxicology"
2021-now, Postgraduate Course "Topics in Veterinary Pharmacology and Toxicology"
British of Pharmacology
Journal of Antimicrobial Chemotherapy
Antimicrobial Agents and Chemotherapy
2020-Now, Editorial Board Member of Evidence-based Complementary and Alternative Medicine
2019-Now, Editorial Board Member of International Journal of Functional Nutrition
Chongshan Dai#, Qinfeng Li, Herman I May, Chao Li, Guangyu Zhang, Gaurav Sharma, A Dean Sherry, Craig R Malloy, Chalermchai Khemtong, Yuannyu Zhang, Yingfeng Deng, Thomas G Gillette, Jian Xu, David T Scadden, Zhao V Wang*; Lactate dehydrogenase A governs cardiac hypertrophic growth in response to hemodynamic stress. Cell Reports, 2020, 32: 108087.
Chongshan Dai#, Xilong Xiao, Daowen Li, Sun Tun, Ying Wang, Tony Velkov*, Shusheng Tan*; Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis. Cell Death & Disease, 2018, 26: 1164.
Tony Velkov#*, Chongshan Dai#, Giuseppe D Ciccotosto, Roberto Cappai, Daniel Hoyer, Jian Li; Polymyxins for CNS infections: pharmacology and neurotoxicity. Pharmacology & Therapeutics, 2018, 181: 85-90.
Chongshan Dai#, Giuseppe D Ciccotosto, Roberto Cappai, Shusheng Tang, Daowen Li, Sanlei Xie, Xilong Xiao*, Tony Velkov*; Curcumin attenuates colistin-induced neurotoxicity in N2a cells via anti-inflammatory activity, suppression of oxidative stress, and apoptosis. Molecular Neurobiology, 2018, 55: 421-434.
Chongshan Dai#, Shusheng Tang, Tony Velkov*, Xilong Xiao*. Colistin-induced apoptosis of neuroblastoma-2a cells involves the generation of reactive oxygen species, mitochondrial dysfunction, and autophagy. Molecular Neurobiology, 2016, 53: 4685-700.
Chongshan Dai#*, Hui Li, Yang Wang, Shusheng Tang, Tony Velkov*, Jianzhong Shen. Inhibition of oxidative stress and alox12 and nf-κb pathways contribute to the protective effect of baicalein on carbon tetrachloride-induced acute liver injury. Antioxidants, 2021,10:976.
Chongshan Dai#*, Yang Wang, Gaurav Sharma, Jianzhong Shen, Tony Velkov, Xilong Xiao*. Polymyxins-curcumin combination antimicrobial therapy: safety implications and efficacy for infection treatment. Antioxidants, 2020, 9: 506.
Chongshan Dai#, Xin Chen, Jingbo Li, Paul Comish, Rui Kang*, Daolin Tang*. Transcription factors in ferroptotic cell death. Cancer Gene Therapy, 2020, 27: 645-656. ESI High citation
Chongshan Dai#, Shusheng Tang, Yang Wang, Tony Velkov, Xilong Xiao*; Baicalein acts as a nephroprotectant that ameliorates colistin-induced nephrotoxicity by activating the antioxidant defence mechanism of the kidneys and down-regulating the inflammatory response. Journal of Antimicrobial Chemotherapy, 2017, 72: 2562-2569.
Chongshan Dai#, Xilong Xiao, Yuan Zhang, Biao Xiang, Daniel Hoyer, Jianzhong Shen, Tony Velkov*, Shusheng Tang*. Curcumin attenuates colistin - induced peripheral neurotoxicity in mice. ACS Infectious Diseases, 2020, 6(4): 715-724. F1000 Prime recommended.