Hanchun Yang, DVM, PhD

Education

• 09/1988-07/1992, PhD in China Agricultural University

• 09/1983-07/1986, MS in Nanjing Agricultural University

• 09/1979-07/1983, DVM in Sichuan Agricultural University

Professional Experience

• 1997-present, Professor, College of Veterinary Medicine, China Agricultural University

• 2000-2001, Visiting Professor, University of Maryland

• 1992-1997, Associate Professor, College of Veterinary Medicine, China Agricultural University

• 1994, Visiting Scholar, The Hebrew University

• 1988-1992, Lecturer, College of Veterinary Medicine, China Agricultural University

• 1986-1988, Assistant Professor, College of Veterinary Medicine, China Agricultural University

Research Interests

• Molecular Etiology, Pathogenesis, Immunity, Diagnosis, and Control and Other Aspects of Swine Viral Diseases

Awards and Honors

• 2014, National Excellent Scientific Workers of CAST, China

• 2012, The National Middle-aged Expert with Outstanding Contribution, China

• 2012, Millions of Talent Projects National candidates, China

• 2011, Outstanding Talents in Agricultural Research of MOA, China

• 2008, The National Science Fund for Distinguished Young Scholars, China

• 2008, Beijing Renowned Teachers

• 2008, Baogang Excellent Teachers

Teaching

• 1987-present, Undergraduate course “Veterinary Immunology”

• 1992-present, Graduate course ”Advances in Veterinary Immunology”

• 1997-present, Graduate course “Seminar in Preventive Veterinary Medicine”

Academic Service

• 2020-present, Editorial Board Member of Pig Health Management

• 2020-present, Academic Editor of BioMed Research International

• 2019-present, Editorial Board Member of Veterinary Sciences

• 2018-present, Chairman of International Pig Veterinary Society (IPVS) Board

• 2016-present, Deputy President of Chinese Association of Animal Science and Veterinary Medicine

• 2016-present, Board Member of International Pig Veterinary Society (IPVS)

• 2011-present, General Secretary of Chinese Association of Animal Science and Veterinary Medicine

• 2003-present, Deputy Editor-In-Chief of Chinese Journal of Animal and Veterinary Sciences

Selected Publications

• Lei Zhou, Xinna Ge, Hanchun Yang*. 2021. Porcine reproductive and respiratory syndrome modified live virus vaccine: A “leaky” vaccine with debatable efficacy and safety. Vaccines. 9: 362.

• Xinrong Zhou, Xinna Ge, Yongning Zhang, Jun Han, Xin Guo, Yanhong Chen, Lei Zhou*, Hanchun Yang*. 2021. Attenuation of porcine deltacoronavirus disease severity by porcine reproductive and respiratory syndrome virus coinfection in a weaning pig model. Virulence. 12 (1): 1011-1021.

• Xinrong Zhou, Lei Zhou, Pingping Zhang, Xinna Ge, Xin Guo, Jun Han, Yongning Zhang*, Hanchun Yang*. 2021. A strain of porcine deltacoronavirus: Genomic characterization, pathogenicity and its full-length cDNA infectious clone. Transboundary and Emerging Diseases. 68 (4): 2130-2146.

• Xinrong Zhou, Lei Zhou, Xinna Ge, Xin Guo, Jun Han, Yongning Zhang*, Hanchun Yang*. 2020. Quantitative proteomic analysis of porcine intestinal epithelial cells infected with porcine deltacoronavirus using iTRAQ-coupled LC-MS/MS. Journal of Proteome Research.19 (11): 4470-4485.

• Zhendong Zhang , Lei Zhou , Xinna Ge, Xin Guo, Jun Han, Hanchun Yang*. 2018. Evolutionary analysis of six isolates of porcine reproductive and respiratory syndrome virus from a single pig farm: MLV-evolved and recombinant viruses. Infection, Genetics and Evolution. 66: 111-119.

• Lei Xu, Lei Zhou, Weifeng Sun, Pingping Zhang, Xinna Ge, Xin Guo, Jun Han, Hanchun Yang*. 2018. Nonstructural protein 9 residues 586 and 592 are critical sites in determining the replication efficiency and fatal virulence of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus. Virology. 517: 135-147.

• Di Wang, Xinna Ge, Dongjie Chen, Jie Li, Yueqi Cai, Jin Deng, Lei Zhou, Xin Guo, Jun Han*, Hanchun Yang*. 2018. The S gene is necessary but not sufficient for the virulence of porcine epidemic diarrhea virus novel variant strain BJ2011C. Journal of Virology. 92 (13): e00603-18.

• Jun Han, Lei Zhou, Xinna Ge, Xin Guo, Hanchun Yang*. 2017. Pathogenesis and control of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus. Veterinary Microbiology. 209: 30-47.

• Lei Zhou, Beina Yang, Lei Xu, Huan Jin, Xinna Ge, Xin Guo, Jun Han, Hanchun Yang*. 2017. Efficacy evaluation of three modified-live virus vaccines against a strain of porcine reproductive and respiratory syndrome virus NADC30-like. Veterinary Microbiology. 207: 108-116.

• Ting Bian, Yingfeng Sun, Meng Hao, Lei Zhou, Xinna Ge, Xin Guo, Jun Han, Hanchun Yang*. 2017. A recombinant type 2 porcine reproductive and respiratory syndrome virus between NADC30-like and a MLV-like: Genetic characterization and pathogenicity for piglets. Infection, Genetics and Evolution. 54: 279-286.

• Jige Du, Xinna Ge , Ying Liu, Ping Jiang, Zhe Wang, Ruimin Zhang, Lei Zhou, Xin Guo, Jun Han*, Hanchun Yang*. 2016. Targeting swine leukocyte antigen class I molecules for proteasomal degradation by the nsp1a replicase protein of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus strain JXwn06. Journal of Virology. 90 (2): 682-693.

• Yan Li, Lei Zhou, Jialong Zhang, Xinna Ge, Rong Zhou, Huaguo Zheng, Gang Geng, Xin Guo, Hanchun Yang*. 2014. Nsp9 and nsp10 contribute to the fatal virulence of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China. PLoS Pathogens. 10 (7): e1004216.

• Yongning Zhang, Zhongchang Li, Xinna Ge, Xin Guo, Hanchun Yang*. 2011. Autophagy promotes the replication of encephalomyocarditis virus in host cells. Autophagy. 7 (6): 613-628.

• Lei Zhou, Jialong Zhang, Jingwen Zeng, Shuoyan Yin, Yanhua Li, Linying Zheng, Xin Guo, Xinna Ge, Hanchun Yang*. 2009. The 30-amino-acid deletion in the nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China Is not related to its virulence. Journal of Virology.83 (10): 5156-5167.