研究领域: 酵母合成生物学,真菌致病机理以及耐药性机制,猫冠状病毒。 工作经历: 2019年7月至今,中国农业大学,动物医学院,副教授,硕士生导师 2017年7月-2019年6月,北京化工大学,高精尖中心,博士后,合作导师:中国工程院外籍院士Jens Nielsen教授 教育背景: 2009年8月-2016年12月,Purdue University,农业学院,生物化学系,获得博士学位,导师:Scott Briggs教授 2005年8月-2009年6月,北京大学,生命科学学院,获得理学学士学位,导师:郑晓峰教授 主持和参加科研项目: 主持国家自然科学基金委青年科学基金项目一项,曾获第12批中国博士后科学基金特别资助,担任重点研发计划(合成生物学)“酿酒酵母基因组深度设计原则研究”课题项目骨干。 代表性文章(#为共同一作,*为通讯作者): [1] Junhao Cheng, Mingkun Wu, Ren Zhong, Dayong Si, Geng Meng, Rijun Zhang*, Yueping Zhang*, Rapid Golden Gate assembly of exons from genomic DNA for protein expression in Escherichia coli and Pichia pastoris. Biotechniques. 2021 Aug 10. doi: https://doi.org/10.2144/btn-2021-0039 [2] Yu Fu, Zhenglin Zhu, Geng Meng, Rijun Zhang*, Yueping Zhang*, A CRISPR‑Cas9 based shuffle system for endogenous histone H3 and H4 combinatorial mutagenesis. Scientific Reports. 2021, Feb 8;11(1):3298, doi: https://doi.org/10.1038/s41598-021-82774-4 [3] Jinyu Fu#, Yueping Zhang#, Guang Cai, Geng Meng*, Shuobo Shi*, Rapid and sensitive RPA-Cas12a-fluorescence assay for point-of-care detection of African swine fever virus. PLoS One. 2021 Jul 19;16(7):e0254815. doi: https://doi.org/10.1371/journal.pone.0254815 [4] Guiping Gong#, Yueping Zhang#, Zibai Wang, Luo Liu, Shuobo Shi, Verena Siewers, Qipeng Yuan, Jens Nielsen, Xu Zhang*, and Zihe Liu*, GTR 2.0: gRNA-tRNA Array and Cas9-NG Based Genome Disruption and Single-Nucleotide Conversion in Saccharomyces cerevisiae. ACS Synthetic Biology. 2021 May 20, doi: https://doi.org/10.1021/acssynbio.0c00560 [5] Yijin Zhao#, Yueping Zhang#, Jens Nielsen, Zihe Liu*, Production of β‐carotene in Saccharomyces cerevisiae through altering yeast lipid metabolism. Biotechnology and Bioengineering. 2021 May;118(5):2043-2052. doi: https://doi.org/10.1002/bit.27717 [6] Yueping Zhang#, Juan Wang#, Zibai Wang, Yiming Zhang, Shuobo Shi, Jens Nielsen, Zihe Liu*, A gRNA-tRNA Array CRISPR-Cas9 Based Rapid Multiplexed Genome Editing in Saccharomyces cerevisiae. Nature Communications. 2019 Mar 5;10(1):1053, doi: https://doi.org/10.1038/s41467-019-09005-3 [7] Zihe Liu, Yueping Zhang, Jens Nielsen*; Synthetic Biology of Yeast. Biochemistry. 2019 Mar 19;58(11):1511-1520, doi: https://doi.org/10.1021/acs.biochem.8b01236 [8] Yueping Zhang, Jens Nielsen, Zihe Liu*, Engineering yeast metabolism for production of terpenoids for use as perfume ingredients, pharmaceuticals and biofuels. FEMS Yeast Research. 2017 Dec 1;17(8), doi: https://doi.org/10.1093/femsyr/fox080 [9] Yueping Zhang, Nina D. Serratore, Scott D. Briggs*, (2017) N-ICE plasmids for generating N-terminal 3×FLAG tagged genes that allow Inducible, Constitutive, or Endogenous expression in Saccharomyces cerevisiae. Yeast. 2017 May;34(5):223-235, doi: https://doi.org/10.1002/yea.3226 |