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基础兽医系

姓名:刘天龙

性别:男

职称:副教授

学位:博士

所在系:基础兽医系

导师类型:博导兼硕导

出生年月:1978.12

电子邮件:liutianlong@cau.edu.cn

办公电话:010-62733398

个人简介

目前主要从事动物病理学的教学和研究工作,研究方向包括戊型肝炎病毒发病机制、野生动物疾病发病机制及防治研究、新型纳米抗菌材料、纳米材料安全性评价和新型纳米抗肿瘤制剂研究等,主持国家自然科学基金和863项目子项目2项,主持北京市自然科学基金面上项目1项,作为主要科研骨干参加863项目和国家自然科学基金共3项,在Biomaterials、Chemical communication,Advanced materials、Angewandte Chemie International Edition、ACS nano等国际知名期刊发表论文共计40余篇,影响因子5以上的25篇,论文引用次数超过1400次,主编和参与出版著作12部。

教育经历

2005/9 - 2008/7,中国农业大学,基础兽医学,博士,导师:佘锐萍

2002/9 - 2005/7,中国农业大学,临床兽医学,硕士,导师:刘钟杰

1998/9 - 2002/7,山东农业大学,动物医学,学士,导师:姜世金

工作经历

2017/3 – 至今,中国农业大学动物医学院,副教授

2012/7 – 2017/2,中国科学院理化技术研究所,副研究员

2010/10-2012/7,中国科学院理化技术研究所,助理研究员

2008/10-2010/10,中国科学院理化技术研究所,博士后

研究领域

纳米材料抗细菌生物膜机制研究、抗菌肽纳米化制剂研究、戊型肝炎病毒发病机制、野生动物疾病发病机制及防治研究、纳米材料安全性评价和新型纳米抗肿瘤制剂研究等

获奖及荣誉

2019年评为北京市优秀本科生毕业论文指导教师,

获得2020年第六届全国大学生动物医学专业技能大赛特等奖优秀指导教师奖。

教学工作

主持2019年北京市优秀虚拟仿真项目1项,

主持两项中国农业大学研究生教改项目。

在研项目

1.北京市自然科学基金项目,6202017,HEV感染诱导卵巢颗粒细胞自噬的分子机制及其在卵巢损伤中的作用,2020.1-2022.12,19万元,在研,主持。

2.国家自然科学基金青年项目,31802162,NLRP3炎症小体在HEV感染致肝脏细胞焦亡过程中的作用机制,2019/01-2021/12,25万元,在研,参加。

代表性文章

1.Luoyan Duan, Lei Zhang, Feiyi Yan, Zhaoping Liu, Huihui Bao, and Tianlong Liu, Solubility of ZnO Nanoparticles in Food Media: An Analysis Using a Novel Semiclosed Dynamic System, Journal of Agricultural and Food Chemistry,2021,(SCI,5.279)

2.Bai, Q.; Wang, Y.; Duan, L.; Xu, X.; Hu, Y.; Yang, Y.; Zhang, L.; Liu, Z.; Bao, H.; Liu, T. Cu-Doped-ZnO Nanocrystals Induce Hepatocyte Autophagy by Oxidative Stress Pathway,Nanomaterials 2021, 11, 2081.(SCI,5.076)

3.Yue Yang,Taya Tang, Bo Liu,Jijing Tian,Haiyan Wu, Zhongjie Liu,Zhaoping Liu, Lei Zhang, Huihui Bao,* Tianlong Liu*, TB@PLGA nanoparticles for photodynamic/photothermal combined cancer therapy with single near-infrared irradiation. INTERNATIONAL JOURNAL OF NANOMEDICINE,2021:16, 4863—4871(SCI,6.4)

4. Lipeng Zhang, Lin Kang, Xianqiang Li, Shiyang Liu, Tianlong Liu, * Yuxia Zhao, *Pyrazino[2,3-g]quinoxaline-Based Nanoparticles as Near-Infrared Phototheranostic Agents for Efficient Photoacoustic-Imaging- Guided Photothermal Therapy,  ACS Appl. Nano Mater. 2021, 4, 2019−2029(SCI,5.097)

5.Jiamin Ni, Yiduo Liu, Tariq Hussain , Miaoxuan Li, Zhengmin Liang, Tianlong Liu,* Xiangmei Zhou*  Recombinant ArgF PLGA nanoparticles enhances BCG induced immune responses against Mycobacterium bovis infection, Biomedicine & Pharmacotherapy 137 (2021) 111341(SCI,6.529)

6.Zhengmin Liang, Yiduo Liu , Xingya Sun, Jingjun Lin, Jiao Yao, Yinjuan Song,Miaoxuan Li , Tianlong Liu,* Xiangmei Zhou*,Immunoregulatory and Antimicrobial Activity of Bovine Neutrophil  β-Defensin-5-Loaded PLGA Nanoparticles against Mycobacterium bovis,Pharmaceutics 2020, 12, 1172.(SCI,6.321)

7.Taya Tang, Xiaomu Xu, Zhiwen Wang, Jijing Tian, Yue Yang, Caizhang Ou, Huihui Bao, Tianlong Liu*.Cu2ZnSnS4 Nanocrystals for Microwave Thermal and Microwave Dynamic CombinationTumor Therapy, Chemical Communications,2019, 55, 13148-13151(SCI,6.222)

8.Caiyun Huo, Jin Xiao, Kai Xiao, Shumei Zou, Ming Wang, Peng Qi, Tianlong Liu*, Yanxin Hu. Pre-Treatment with Zirconia Nanoparticles Reduces Inflammation Induced by the Pathogenic H5N1 Influenza Virus,INTERNATIONAL JOURNAL OF NANOMEDICINE,2020,15:661—674(SCI,6.4)

9.Xiaomu Xu, Yusheng Hu, Li-peng Zhang, Bo Liu, Yue Yang, Taya Tang, Jijing Tian, Kaisong Peng and Tianlong Liu*. Lactic-co-glycolic acid-coated methylene blue nanoparticles with enhanced antibacterial activity for efficient wound healing, RSC Advances,2019, 55, 13148-13151(SCI,IF=3.361)

10.Yang, Yue; Bao, Huihui; Chai, Qianqian, Zhiwen Wang, Zhenning Sun, Changhui Fu,  Zhaoping Liu, Zhongjie Liu, Xianwei Meng, Tianlong Liu*, Toxicity, biodistribution and oxidative damage caused by zirconia nanoparticles after intravenous injection. INTERNATIONAL JOURNAL OF NANOMEDICINE,2019, 14:‏ 5175-5186 ‏(SCI,IF=6.4)

11.Tianlong Liu, Peng Xiao, Ruiwen Li, Ruiping She, Jijing Tian, Jingyuan Wang,Jingjing Mao, Jun Yin, Ruihan Shi, Increased mast cell activation in Mongolian gerbils infected by hepatitis E virus. Frontiers in microbiology,2018(9):2226-2232 (SCI, IF=5.64

12.Longfei Tan, Wenting Tang, Tianlong Liu(并列通讯), Xiangling Ren, Changhui Fu, Bo Liu, Jun Ren and   Xianwei Meng, Biocompatible Hollow Polydopamine Nanoparticles Loaded Ionic   Liquid Enhanced Tumor Microwave Thermal Ablation in Vivo. ACS Applied Materials &Interfaces,2016,11237-11245. (SCI, 9.229)

13.Haitang Shi,Tianlong Liu (并列第一),Changhui Fu,Linlin Li,Longfei Tan,JingzhuoWang,Xiangling Ren,Jun Ren,Jianxin Wang,Xianwei Meng,Insights into a microwave susceptible agent for minimally invasive,Biomaterials,2015,44:91-102. (SCI,12.479)

14.Xiangyang Bai,Linlin Li,Huiyu Liu,Longfei Tan,Tianlong Liu(并列通讯),Xianwei Meng,SolvothermalSynthesis of ZnO Nanoparticles and   Anti-Infection Application in Vivo,ACS Applied Materials &Interfaces,2014,(7):1308-1317.(SCI, 9.229)

15.Tianlong Liu, Linlin Li, Changhui Fu, Huiyu Liu, Dong Chen and Fangqiong Tang. Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles. Biomaterials,2012,33,2399-2407 (SCI,12.479)

16.Tianlong Liu, Linlin Li, Xu Teng, Xinglu Huang, Huiyu Liu, Dong Chen, Jun Ren, Junqi He, Fangqiong Tang, Single and repeated dose toxicity of mesoporous hollow silica nanoparticles in intravenously exposed mice, Biomaterials, 2011, 32, 1657-1668. (SCI,12.479)