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>> 师资队伍 >> 师资队伍 >> 预防兽医系 >> 教授
姓名:潘保良 性别: 职务:
所在系:预防兽医系 职称:教授 导师类别:博导/硕导
政治面貌:中共党员 出生年月:1974.07. 学位:博士
电子邮件:baoliang@cau.edu.cn 办公电话:010-62734098

个人简介:

潘保良,中国农业大学动物医学院 教授/博导,中国畜牧兽医学会兽医寄生虫学分会 副秘书长/常务理事。籍贯:湖南省宁乡县。  

教育背景:  

1994年-- 1998年   中国农业大学   攻读兽医学学士学位,获学士学位

1998年-- 2000   中国农业大学   攻读预防兽医学硕士学位,获硕士学位

2000年-- 2003   中国农业大学   攻读预防兽医学博士学位,获博士学位

工作经历:

200307月-200310    中国农业大学动物医学院,助教

2003年11月-200512    中国农业大学动物医学院,讲师

2006年01月-201312    中国农业大学动物医学院,副教授

2011年02月-201202    英国爱丁堡大学Roslin研究所,访问学者

2014年01月-        中国农业大学动物医学院,教授

科研项目:

承担或参加的科研项目。

项目名称

项目来源

项目编号

起止年月

本人作用

鸡皮刺螨聚集的化学通讯机制研究

国家自然科学基金

32072882

2021.01-2024.12

主持人

鸡皮刺螨体表疏水性机制及对杀虫药液渗入的阻止作用

国家自然科学基金

31873008

2019.01-2022.12

主持人

家畜寄生虫病防控新制剂和合理用药新技术

国家重点研发计划

2017YFD0501206

2017.07-2020.12

子课题主持人

牦牛重要疫病防控技术集成与应用

国家重点研发计划

2018YFD0502305

2018.06-2020.12

子课题主持人

国家奶牛产业技术体系

国家产业技术体系

CARS-37

2008-2017

主要参加人

放牧动物蠕虫病防控技术研究与示范

国家公益性行业科研专项

201303037

2013.01-2017.12

主持人

Research   and Development of a Long-acting Injectable Suspension of Ivermectin to   Control Parasites in Ruminant Livestock in South Asia, sub-Saharan Africa and   China.

BILL   & MELINDA GATES foundation

OPP1088557

2013.01-2017.12

主持人

北京地区皮刺螨传播蛋鸡常见细菌性疾病的作用研究

北京市自然科学基金

6092012

2009.01-2011.12

主持人

动物粪便中伊维菌素的微生物降解

国家自然科学基金

30600449

2007.01-2009.12

主持人

伊维菌素长效注射液的研制与开发

863子课题

2006AA10A208-2-1

2006.12-2010.10

主持人

奶牛主要疫病快速诊断技术研究和疫苗的研制

国家科技支撑计划

2006BAD04A05-03

2006.01-2010.12  

主持人

新兽药研制开发与抗药性检测技术研究

国家十五攻关

2004BA514A20

2004.06-2005.12

主要参加人

乙酰氨基阿维菌素的研制

国家十五攻关

2004BA514A20-01

2004.06-2005.12

主持人

科研业绩:

主要从事外寄生虫生物学、寄生虫病防治新技术研究和抗寄生虫新兽药及新制剂的研制。研制出奶牛专用抗寄生虫新药——乙酰氨基阿维菌素原料药、注射液、浇泼剂,获国家新兽药证书;制定出乙酰氨基阿维菌素原料药质量标准、注射液和浇泼剂质量标准,被农业部颁布为行业标准。建立牛奶中乙酰氨基残留检测方法,被农业部和卫生部颁布为国家标准(草案)。乙酰氨基阿维菌素是一种可应用于奶牛且不需休药期的广谱抗寄生虫药,有利于提高我国奶牛寄生虫的防治水平,减少因寄生虫感染给奶牛养殖业造成的经济损失。 

利用固体分散体技术和混悬剂技术,开展抗寄生虫长效制剂的研制,长效伊维菌素注射剂的研制获得Bill & Melinda Gates Foundation资助;研制出阿维菌素长效注射液(油悬剂),已被投入生产使用;研制出微环境改良妥曲珠利固体分散体,并制备出混悬剂。长效制剂可以有效防止动物寄生虫的反复感染,减少动物用药次数,方便用药。参与吡喹酮纳米注射剂的研制。利用原位凝胶技术,研制吡喹酮原位凝胶注射剂。

开展蜱、螨等媒介节肢动物的生物学和在疾病传播中的作用研究。在国内外率先建立起成熟可靠的鸡皮刺螨实验室养殖系统,开展鸡皮刺螨聚集机制(聚集信息素)、卵发育机制、抗药性研究和疫苗研制;从鸡螨虫中分离出数种致病菌,证实鸡螨虫是鸡场常见细菌的重要传播者,是重要的病原库,为鸡场细菌病的防治提供了新的依据。开展蜱生态学研究和传播疾病研究,将为我国蜱的防治提供技术支撑。

发表学术论文100多篇,其中SCI收录论文36篇;参与制定出部颁标准4项。参与编著/编译著作18部。“奶牛专用广谱抗寄生虫药-乙酰氨基阿维菌素的研制”获大北农科技成果奖。“偶蹄家畜重大和常发疫病防治关键技术研究与推广”获“北京市农业技术推广”一等奖。

部分英文文章

1)Xiaolin Xu, Chuanwen Wang, Yu Huang, Shudong Zhang, He Yu, Jiali Meng, Baoliang Pan. Evaluation of the vaccine efficacy of three digestive protease antigens from Dermanyssus gallinae using an in vivo rearing system.Vaccine.2020.10.010 (in proof)

2)Chuanwen Wang,  Xiaolin Xu, Yu Huang, He Yu, Hao Li, Qiang Wan, Huan Li, Lianyu Wang, Yanyan Sun, Baoliang Pan. Susceptibility of Dermanyssus gallinae from China to acaricides and functional analysis of glutathione S-transferases associated with beta-cypermethrin resistance. Pesticide Biochemistry and Physiology (in proof).

3)Yu Huang, Huan Li, Chuanwen Wang, Xiaolin Xu, He Yu, Jali Meng, Xiaoxiao Qi, Bohan Wang, Baoliang Pan. De novo assembly and discovery of genes related to blood digestion in the transcriptome of Dermanyssus gallinae (Acari: Dermanyssidae). Veterinary Parasitology. 2020, 286:109246.

4)Huan Li, Yu Huang, Jingwei Wang, He Yu, Jiayi Zhao, Qiang Wan, Xiaoxiao Qi, Hao Li, Chuanwen Wang, Baoliang Pan. Molecular and biochemical characterization of enolase from Dermanyssus gallinae. Gene. 2020, 756:144911

5)Chuanwen Wang, Xiaolin Xu, He Yu, Yu Huang, Qiang Wan, Hao Li, Baoliang Pan. Low-Temperature Storage of the Poultry Red Mite, Dermanyssus gallinae, Facilitates Colony Mantainance and Population Growth. Parasitology. 2020, 147(7):740-746.

6)Chuanwen Wang, Xiaolin Xu, Yu Huang, He Yu, Hao Li, Qiang Wan, Baoliang Pan. Characterization of Dermanyssus gallinae cytochrome P450 genes and their transcription profiling involved in beta-cypermethrin resistance. Veterinary Parasitology. 2020, ‏ 283: 109155

7)Li, Hao; Li, Jie; Wan, Qiang; et al. Monensin biodegradation pathway and role of epoxide hydrolase in Stenotrophomonas maltophilia DM-2. Journal of Chemical Technology & Biotechnology. 2020, 95(6): 1825-1833

8)Chuanwen Wang, Yu Huang, Jiayi Zhao, Yuyun Ma, Xiaolin Xu, Qiang Wan, Hao Li, Baoliang Pan. First record of Aspergillus oryzae as an entomopathogenic fungus against the poultry red mite Dermanyssus gallinae. Veterinary Parasitology. 2019, 271:57-63. 

9)Xiaolin Xu, Chuanwen Wang, Shudong Zhang, Yu Huang, Tingting Pan, Bohan Wang, Baoliang Pan*. Acaricidal efficacy of orally administered Macrocyclic Lactones against poultry red mites (Dermanyssus gallinae) on chicks and their impacts on mite reproduction and blood meal digestion. Parasites & Vectors. 2019,12(1):345. 

10)Wan Q, Zhao J, Li H, Li H, Wang C, Pan B. The wetting behavior of three different types of aqueous surfactant solutions on housefly (Musca domestica) surfaces. Pest Manag Sci. 2019 doi: 10.1002/ps.5620.

11)Chuanwen Wang, Yuyun Ma, Yu Huang, Shanchun Su, Lianyu Wang, Yanyan Sun, Qiang Wan, Hao Li, Shudong Zhang, Øivind Øines, Baoliang Pan. Darkness increases the population growth rate of the poultry red mite, Dermanyssus gallinae. Parasites & Vectors. 2019, 12:213 (IF 3.163)

12)Wan Q, Li H, Zhang S, Wang C, Su S, Long S, Pan B. Combination of active behaviors and passive structures contributes to the cleanliness of housefly wing surfaces: A new insight for the design of cleaning materials. Colloids Surf B Biointerfaces. 2019, 180: 473-480.  (IF 3.997)

13)Zhang S, Wan Q, Xu X, Xing Y, Ding J, Yang S, Sun W, Lu M, Pan B. A novel oil-based suspension of a micro-environmental, pH-modifying solid dispersion for parenteral delivery: Formulation and stability evaluation. Colloids Surf B Biointerfaces. 2019, 179:382-392. (IF 3.997)

14)Shudong Zhang, Qiang Wan, Yidan Xing, Jiafeng Ding, Shizhuang Yang, Weiwei Sun, Mengmeng Lu, Baoliang Pan. Formulation and evaluation of a novel oral oil-based suspension using micro-environmental pH-modifying solid dispersion. AAPS PharmSciTech. 2019, 20(2):75. (IF 2.666)

15)Hao Li, Qiang Wan, Shudong Zhang, Chuanwen Wang, Shanchun Su, Baoliang Pan. Housefly larvae (Musca domestica) significantly accelerates degradation of monensin by altering the structure and abundance of the associated bacterial community. Ecotoxicology and Environmental Safety. 2019,170: 418–426. (IF 3.974)

16)Lu M, Cai Y, Yang S, Wan Q, Pan B. A single subcutaneous administration of a sustained-release ivermectin suspension eliminates Psoroptes cuniculi infection in a rabbit farm. Drug Dev Ind Pharm. 2018, 19:1-5.

17)Chuanwen Wang, Yuyun Ma, Yu Huang, Jianhai Xu, Jinzhong Cai, Baoliang Pan. An efficient rearing system rapidly producing large quantities of poultry red mites, Dermanyssus gallinae (Acari: Dermanyssidae), under laboratory conditions. Veterinary Parasitology, 2018,258:38–45. 

18)Sun W, Pan B. Effect of micro-environment modification and polymer type on the in-vitro dissolution behavior and in-vivo performance of amorphous solid dispersions. Eur J Pharm Sci. 2017, 104:240-254.  

19)Lu M, Xiong D, Sun W, Yu T, Hu Z, Ding J, Cai Y, Yang S, Pan B. Sustained release ivermectin-loaded solid lipid dispersion for subcutaneous delivery: in vitro and in vivo evaluation. Drug Deliv. 2017, 24(1):622-631. 

20)Yu T, Shi YL, Cai JZ, Li CH, Lei MT, Pan BL, Wang M. Plasma kinetics, excretion in milk of eprinomectin, and its efficacy against Hypoderma spp. following topical administration in yaks. J Vet Pharmacol Ther. 2015, 38(6):563-568.

21)Xie S, Pan B, Shi B, Zhang Z, Zhang X, Wang M, Zhou W. Solid lipid nanoparticle suspension enhanced the therapeutic efficacy of praziquantel against tapeworm. Int J Nanomedicine. 2011, 6:2367-74.  

22)Pan B, Wen H, Yang Z, Wang F, Wang Z, Wang M. Pharmacokinetics of moxidectin following topical administration to New Zealand rabbits. J Vet Pharmacol Ther. 2011, 34(1):89-91.  

23)Xie, S.Y., Pan, B., wang M., Zhu, L.Y., Wang F.H., Dong,Z, Wang, X.F., Zhou, W.Z., Formulation, characterization and pharmacokinetics of praziquantel-loaded hydrogenated castor oil-solid lipid nanoparticles. Nanomedicine. 2010, 5(5): 693–70. 

24)Wen H, Pan B, Wang F, Yang Z, Wang Z, Liu S, Wang M. The effect of self-licking behavior on pharmacokinetics of eprinomectin and clinical efficacy against Psoroptes cuniculi in topically administered rabbits. Parasitol Res. 2010, 106(3):607-13. 

25)Wen H, Pan B, Wang Y, Wang F, Yang Z, Wang M. Plasma and milk kinetics of eprinomectin following topical or oral administration to lactating Chinese Holstein cows. Vet Parasitol. 2010,174(1-2):72-6.   

26)Wang FF, Wang M, Xu FR, Liang DM, Pan BL. Survey of prevalence and control of ectoparasites in caged poultry in China. Vet Rec. 2010, 167(24):934-7.  

27)Pan B, Liang D, Zhang Y, Wang H, Wang M. Comparative efficacy of oil solution and wettable powder of lambda-cyhalothrin to naturally occurring Ornithonyssus sylviarum infestation of chickens. Vet Parasitol. 2009, 164: 353–356.  

28)Pan BL, Zhang YF, Suo X, Xue Y. Effect of subcutaneously administered diclazuril on the output of Eimeria species oocysts by experimentally infected rabbits. Vet Rec. 2008, 162(5):153-155.  

29)Xu FR, Pan BL, Wang YW, Pan ZD, Dai XX, Liu PH, Wang M. Pharmacokinetics of injectable long-acting ivermectin aqueous suspension following subcutaneous administration in sheep. J Vet Pharmacol Ther. 2007,30(5):486-488. 

30)Baoliang Pan, Yuwan Wang, Zhende Pan, Adrian Luis Lifschitz, Ming Wang. Pharmacokinetics of Eprinomectin in Plasma and Milk following Subcutaneous Administration to Lactating Dairy Cattle. Vet Res Commun. 2006,30(3):263-270.  

31)Pan B, Wang M, Xu F, Wang Y, Dong Y, Pan Z. Efficacy of an injectable formulation of eprinomectin against Psoroptes cuniculi, the ear mange mite in rabbits. Vet Parasitol. 2006, 137(3-4):386-390.  

教学工作:

本科教学——参讲2门国家精品课程《兽医寄生虫学》(网络课程)和《兽医寄生虫学》(本科生课程)。《兽医寄生虫学》(网络课程)获北京市教学成果二等奖和中国农业大学教学成果一等奖,教学团队被评为北京市高等学校继续教育优秀教学团队和北京高校继续教育重点建设教学团队。

研究生教学——主讲研究生课程《畜禽寄生虫病防治技术》和《兽医寄生虫学试验技术》。《兽医寄生虫学试验技术》被列为中国农业大学研究生重点建设课程。

研究生培养理念:

搭建良好平台,营造浓厚学术氛围,促进学生快乐成长。



 

 

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E-mail: vetli@cau.edu.cn