个人简介：

高健，2012年6月中国农业大学临床兽医学博士毕业；2012年8月至2013年12月在首农畜牧从事奶牛养殖工作；2014年1月至2016年3月在中国农业大学生物学院从事博士后研究工作；2016年3月至今在中国农业大学动物医学院临床兽医系从事教学、临床诊疗及科学研究工作。主要教学及科研方向为动物产科疾病，包括动物繁殖性疾病、围产期常见病、奶牛乳房炎、新生仔畜疾病等。主讲《大动物临床病例分析》、《奶牛围产期管理》、《疫病防控》等课程；参讲《兽医产科学》、《兽医产科学专题》、《临床兽医专业Seminar》、《兽医内科学专题》、《大动物内科进阶训练》、《临床兽医专业英语》等课程。

近年来，主持或参与国家自然基金、北京市自然基金、国家重点研发计划子课题及企业合作横向项目等各类课题10余项。研究结果在《Veterinary Research》、《Journal of Dairy Science》、《Veterinary Microbiology》等Top期刊发表，累计发表SCI论文及中文期刊论文60余篇；其中以第一或通讯作者发表40余篇。此外，主持2项校级教学改革项目，发表教改论文1篇。获得“中国农业大学第十一届青年教师教学基本功比赛”一等奖，“北京市第十一届青年教师教学基本功比赛”三等奖。

在社会服务方面，担任Journal of Dairy Science、Emerging Microbes & Infections、Peer J、Journal of Applied Microbiology、Animals、《中国农业大学学报》、《农业生物技术学报》等杂志的审稿人；担任奶牛产业扶贫工作站北京科技特派员、中国农业农村部对发展中国家畜牧业生产与管理技术培训班的授课教师、中国农垦标杆牧场评审组专家等。

代表论文（*通讯作者）

1.Cheng, J., J. Zhang, J. Yang, B. Yi, G. Liu, M. Zhou, J. P. Kastelic, B. Han*, and J. Gao*. 2021. Klebsiella pneumoniae infection causes mitochondrial damage and dysfunction in bovine mammary epithelial cells. Vet Res 52(1):17.

2.Cheng, J., M. Zhou, D. B. Nobrega, H. W. Barkema, S. Xu, M. Li, J. P. Kastelic, Y. Shi, B. Han*, and J. Gao*. 2021. Genetic diversity and molecular epidemiology of outbreaks of Klebsiella pneumoniae mastitis on two large Chinese dairy farms. J Dairy Sci 104(1):762-775.

3.Chen, P., Y. Qiu, G. Liu, X. Li, J. Cheng, K. Liu, W. Qu, C. Zhu, J. P. Kastelic, B. Han*, and J. Gao*. 2021. Characterization of Streptococcus lutetiensis isolated from clinical mastitis of dairy cows. J Dairy Sci 104(1):702-714.

4.Zhao, W., Y. Shi, G. Liu, J. Yang, B. Yi, Y. Liu, J. P. Kastelic, B. Han*, and J. Gao*. 2021. Bacteriophage effectively treats a murine mastitis model induced by Klebsiella pneumoniae isolated from bovine mastitis. J Dairy Sci. DOI:10.3168/jds.2020-19094.

5.Shi Y., W. Zhao, L. Gang, T. Ali, P. Chen, Y Liu, J. P. Kastelice, B. Han*, and J Gao*. 2021. Bacteriophages isolated from dairy farm mitigated Klebsiella pneumoniae-induced inflammation in bovine mammary epithelial cells cultured in vitro. BMC Vet Res. DOI:10.1186/s12917-020-02738-0.

6.Cheng, J., J. Zhang, B. Han, H. W. Barkema, E. R. Cobo, J. P. Kastelic, M. Zhou, Y. Shi, J. Wang, R. Yang, and J. Gao*. 2020. Klebsiella pneumoniae isolated from bovine mastitis is cytopathogenic for bovine mammary epithelial cells. J Dairy Sci 103(4):3493-3504.

7.Zhuang, C., G. Liu, H. W. Barkema, M. Zhou, S. Xu, S. Ur Rahman, Y. Liu, J. P. Kastelic, J. Gao*, and B. Han*. 2020. Selenomethionine suppressed TLR4/NF-kappaB pathway by activating selenoprotein S to alleviate ESBL Escherichia coli-induced inflammation in bovine mammary epithelial cells and macrophages. Frontiers in microbiology 11:1461.

8.Rakib, M.R.H., M. Zhou, S. Xu, Liu Y, K.M. Asfandyar, B. Han, and J. Gao*. 2020. Effect of heat stress on udder health of dairy cows. J Dairy Res. DOI:10.1017/S0022029920000886.

9.Gao, J., S. Li, J. Zhang, Y. Zhou, S. Xu, H. W. Barkema, D. B. Nobrega, C. Zhu, and B. Han. 2019. Prevalence of potential virulence genes in Klebsiella spp. isolated from cows with clinical mastitis on large chinese dairy farms. Foodborne Pathog Dis 16(12):856-863.

10.Liu, G., J. Yin, B. Han, H. W. Barkema, M. Shahid, J. De Buck, E. R. Cobo, J. P. Kastelic, and J. Gao*. 2019. Adherent/invasive capacities of bovine-associated Aerococcus viridans contribute to pathogenesis of acute mastitis in a murine model. Vet Microbiol 230:202-211.

11.Qu, Y., H. Zhao, D. B. Nobrega, E. R. Cobo, B. Han, Z. Zhao, S. Li, M. Li, H. W. Barkema, and J. Gao*. 2019. Molecular epidemiology and distribution of antimicrobial resistance genes of Staphylococcus species isolated from Chinese dairy cows with clinical mastitis. J Dairy Sci 102(2):1571-1583.

12.Liu, G., L. Ding, B. Han, S. Piepers, S. A. Naqvi, H. W. Barkema, T. Ali, S. De Vliegher, S. Xu, and J. Gao*. 2018. Characteristics of Escherichia coli isolated from bovine mastitis exposed to subminimum inhibitory concentrations of cefalotin or ceftazidime. BioMed research international 2018:4301628.

13.Ur Rahman, S., T. Ali, I. Ali, N. A. Khan, B. Han, and J. Gao*. 2018. The growing genetic and functional diversity of extended spectrum beta-lactamases. BioMed research international 2018:9519718.

14.Gao, J., H. W. Barkema, L. Zhang, G. Liu, Z. Deng, L. Cai, R. Shan, S. Zhang, J. Zou, J. P. Kastelic, and B. Han. 2017. Incidence of clinical mastitis and distribution of pathogens on large Chinese dairy farms. J Dairy Sci 100(6):4797-4806.

15.Chen, W., Y. Liu, J. Yin, Y. Deng, T. Ali, J. Zhang, J. Cheng, S. Ur Rahman, J. Gao*, and B. Han＊. 2017. Cloning, expression, and immunogenicity of Fimbrial-f17a subunit vaccine against Escherichia coli isolated from bovine mastitis. BioMed research international 2017:3248483.