国家自然科学基金优秀青年基金和中国青年科技奖获得者,入选国家“高层次人才支持计划”青年人才和教育部高层次人才计划,获北京市自然科学一等奖(第三完成人)。2006年以来一直从事细菌耐药性的产生、传播和控制技术的研究,相关研究成果以第一或通讯作者(含共同)在Lancet Infectious Diseases、Nature Microbiology等国际权威杂志发表SCI论文68篇,申请或获得相关专利10项。主持国家重点研发计划、国家自然科学基金重点、国际(地区)合作等项目7项;参加编写中英文专著4部;担任中国畜牧兽医学会兽医药理与毒理学分会常务理事;兼任《中国兽医杂志》副主编、中国工程院院刊《Engineering》客座编辑、英国抗菌药物化疗协会杂志《Journal of Antimicrobial Chemotherapy》编辑、《中国兽医学报》编委、《Animal Disease》编委、美国微生物协会杂志《Antimicrobial Agents and Chemotherapy》编委。 学习经历: 1999年9月- 2003年6月,湖南农业大学,动物医学,学士 2003年9月- 2006年6月,华南农业大学,基础兽医学,硕士 2006年9月- 2009年12月,中国农业大学,基础兽医学,博士 2008年9月-2009年9月,美国爱荷华州立大学,预防兽医与微生物学,联合培养博士 工作经历: 2010年5月-2012年12月,中国农业大学,动物医学院基础兽医系,讲师 2013年1月-2016年12月,中国农业大学,动物医学院基础兽医系,副教授 2017年1月至今,中国农业大学,动物医学院基础兽医系,教授 在研科研项目: 1. 2018-2021:“十三五”国家重点研发计划:畜畜禽药物的代谢转归和耐药性形成机制研究(批准号:2018YFD0500300,1413万),主持 2. 第四批国家“高层次人才支持计划”青年人才,2019入选,238万 3. 2020-2024:国家自然科学基金重点项目:可转移tet(X)变异体介导替加环素高水平耐药的产生与传播机制(批准号:31930110,294万),主持 4. 2019-2022:国家自然科学基金国际(地区)交流与合作项目(组织间合作研究—NSFC-UKRI_MRC(中英)):肠杆菌科细菌广泛耐药株/耐药基因在动物及相关环境的传播与影响研究,(批准号:81861138051,300万),主持 代表性论文(#第一作者,*通讯作者) 1. Fu Y#, Chen Y#, Liu D, Yang D, Liu Z, Wang Y, Wang J, Wang X, Xu X, Li X, He J, Jiang J, Zhai W, Huang L, He T, Xia X, Cai C, Wang Y*, Jiang H*. Abundance of tigecycline resistance genes and association with antibiotic residues in Chinese livestock farms. Journal of Hazard Materials.2021, 409:124921. 2. Wang Y#, Xu C#, Zhang R#, Chen Y#, Shen Y#, Hu F#, Liu D, Lu J, Guo Y, Xia X, Jiang J, Wang X, Fu Y, Yang L, Wang J, Li J, Cai C, Yin D, Che J, Fan R, Wang Y, Qing Y, Liao K, Chen H, Zou M, Liang L, Tang J, Shen Z, Wang S, Yang X, Wu C, Xu S*, Walsh TR*, Shen J*. Changes in colistin resistance and mcr-1 abundance in Escherichia coli of animal and human origins following the ban of colistin-positive additives in China: an epidemiological comparative study. The Lancet Infectious Disease. 2020, 20(10):1161-1171.
3. He T#, Wang R#, Liu D#, Walsh TR, Zhang R, Lv Y, Ke Y, Ji Q, Wei R, Liu Z, Shen Y, Wang G, Sun L, Lei L, Lv Z, Li Y, Pang M, Wang L, Sun Q, Fu Y, Song H, Hao Y, Shen Z, Wang S, Chen G, Wu C, Shen J*, Wang Y*. Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans. Nature Microbiology. 2019, 4:1450-1456.
4. Li J#, Bi Z#, Ma S#, Chen B#, Cai C, He J, Schwarz S, Sun C, Zhou Y, Yin J, Hulth A, Wang Y, Shen Z, Wang S, Wu C, Nilsson LE, Walsh TR, Börjesson S, Shen J, Sun Q*, Wang Y*. Inter-host transmission of carbapenemase-producing Escherichia coli among humans and backyard animals. Environmental Health Perspectives. 2019, 127(10):107009.
5. Zou ZY#, Lei L#, Chen QY, Wang YQ, Cai C, Li WQ, Zhang Z, Shao B*, Wang Y*. Prevalence and dissemination risk of antimicrobial-resistant Enterobacteriaceae from shared bikes in Beijing, China. Environment International. 2019, 132:105119.
6. Shen Y#, Lv Z#, Yang L #, Liu D #, Ou Y, Xu C, Liu W, Yuan D, Hao Y, He J, Li X, Zhou Y, Walsh TR, Shen J, Xia J, Ke Y* and Wang Y*. Integrated Aquaculture Contributes to the Transfer of MCR-1 Between Animals and Humans Via the Aquaculture Supply Chain. Environment International. 2019, 130:104708.
7. Shen Y#, Zhou H#, Xu J, Wang Y, Zhang Q, Walsh TR, Shao B, Wu C, Hu Y, Yang L, Shen Z, Wu Z, Sun Q, Ou Y, Wang Y, Wang S, Wu Y, Cai C, Li J, Shen J*, Zhang R*, Wang Y*. Anthropogenic and environmental factors associated with high prevalence of mcr-1 carriage in humans across China. Nature Microbiology. 2018,3(9):1054-1062.
8. Wang X, Wang Y, Zhou Y, Li J, Yin W, Wang S, Zhang S, Shen J, Shen Z*, Wang Y*. Emergence of a novel mobile colistin resistance gene, mcr-8, in NDM-producing Klebsiella pneumoniae. Emerging Microbes & Infections. 2018, 7(1): 122 2018.07.04.
9. Wang Y#, Tian GB#, Zhang R#, Shen Y#, Tyrrell JM, Huang X, Zhou H, Lei L, Li HY, Doi Y, Fang Y, Ren H, Zhong LL, Shen Z, Zeng KJ, Wang S, Liu JH, Wu C, Walsh TR*, Shen J*. Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study. Lancet Infectious Diseases. 2017, 17:390-399.
10. Wang Y#, Zhang R#, Li J, Wu Z, Yin W, Schwarz S, Tyrrell JM, Zheng Y, Wang S, Shen Z, Liu Z, Liu J, Lei L, Li M, Zhang Q, Wu C, Zhang Q, Wu Y, Walsh TR*, Shen J*. Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production. Nature Microbiology. 2017, 2:16260.
11. Yin W, Li H, Shen Y, Liu Z, Wang S, Shen Z, Zhang R, Walsh TR, Shen J, Wang Y*. Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli. mBio. 2017, 8 (3), e00543-17.
12. Liu YY#, Wang Y#, Walsh TR, Yi LX, Zhang R, Spencer J, Doi Y, Tian G, Dong B, Huang X, Yu LF, Gu D, Ren H, Chen X, Lv L, He D, Zhou H, Liang Z, Liu JH*, Shen J*. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infectious Diseases. 2016, 16(2):161-168.
13. Wang Y#, Lv Y#, Cai J#, Schwarz S#, Cui L, Hu Z, Zhang R, Li J, Zhao Q, He T, Wang D, Wang Z, Shen Y, Li Y, Feβler AT, Wu C, Yu H, Deng X, Xia X, Shen J*. A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin. Journal of Antimicrobial Chemotherapy. 2015, 70:2182-2190.
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