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Evolution of Phagocytic B Cells: Innate or Adaptive?

发布日期:2014-07-10访问次数: 信息来源:动物医学院字号:[ ]

报告人:李军副教授

报告时间:2014711日(周五)下午4:00-6:00

报告地点:动医动科大楼四层会议室401

联系人:夏春,陈兆叁

联系电话:010-6273337215210922040

 

李军副教授简介

 

学历:

1998-2002,博士(鱼类生理学和病理学)香港中文大学生物系,香港

1992-1995,硕士(鱼类遗传学)中科院水生生物研究所,武汉.

1988-1992,学士(微生物学与免疫学)武汉大学生物系, 武汉

 

研究经历:

1995, 8 – 2002, 4       中国海洋大学生命学院,助教,讲师

1996, 11–1997, 5       香港中文大学生物系,          访问学者

2001, 1 – 2002, 1       法国Universite Paul Sabatier,      博士后

2002, 4 – 2009, 10     美国宾西法尼亚大学        Research associate

2009, 11 – 2013, 10   美国Lake Superior State University, 助理教授

2013, 11- 至今美国Lake Superior State University,副教授

 

科研兴趣:

.鱼类感染与免疫基础理论研究

.鱼类疾病的免疫防治及疫苗研制开发

 

主要研究论文:

1. David Parra, Jun Li, Aja Rieger, Yong-An Zhang, Louise Randall, Christopher Hunter, Daniel Barreda, J. Oriol Sunyer. 2012. Peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities, and present phagocytosed antigen to CD4+ T cells, Journal of Leukocyte Biology, 91(4) :525-536.

2. Zhang YA, Salinas I., Li J.,  Parra D., Bjork S., LaPatra S.E., Bartholomew J., and Sunyer J.O. 2010. IgT, a primitive immunoglobulin class specialized in mucosal immunity. Nature Immunology, 11:827-835.

3. Li J, Barreda DR, Zhang YA, Boshra H, Gelman AE, LaPatra S, Tort L and Sunyer JO. 2006. B lymphocytes from early vertebrates display potent phagocytic and micribicidal abilities. Nature Immunology, 7, 1116-1124.

4. Wang C, Hu Y, Sun B, Li J, Sun L. 2013. Edwardsiella tarda Ivy: a lysozyme inhibitor that blocks thelytic effect of lysozyme and facilitates host infection in amanner that depends on the conserved cysteine residue. Infection & Immunity. (Published online ahead of print) doi:10.1128/IAI.00503-13.

5. Wang C, Hu Y, Sun B, Chi H, Li J, Sun L. 2013. Environmental isolates P1SW and V3SW as a bivalent vaccine induce effective cross-protection against Edwardsiella tarda and Vibrio anguillarum. Diseases of Aquatic Organisms. 103:45-53.

6. Yu L, Sun B, Li J, Sun L. 2013. Characterization of a c-type lysozyme of Scophthalmus maximus: expression, activity, and antibacterial effect. Fish & Shellfish Immunology. 34: 46-54.

7. Qiu R, Sun B, Li J, Liu X, Sun L. 2013. Identification and characterization of a cell surface scavenger receptor cysteine-rich protein of Sciaenops ocellatus: bacterial interaction and its dependence on the conserved structural features of the SRCR domain. Fish & Shellfish Immunology. 34:810-818.

8. Li M, Chen C, Li J, Sun L. 2013. The C-reactive protein of tongue sole Cynoglossus semilaevisis an acute phase protein that interacts with bacterial pathogens and stimulates the antibacterial activity of peripheral blood leukocytes. Fish & Shellfish Immunology. 34: 623-631.

 





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