从事畜牧兽医学基础兽医领域兽药毒理学和药理学方向，对动物源食品快速检验方法的研究。任全国无公害农产品认证评审委员会委员。

参与国家科技支撑计划课题、973计划课题、863计划课题以及国家自然科学基金项目。参与十余种农业部行业标准制订项目，均已颁布实施。

参加农业部兽药安全监督检验测试中心（北京）承担的农业部农产品质量安全例行监测工作，对全国动物性食品中的兽药残留进行抽查检测，并上报农业部。

北京市科学技术奖一等奖“玉米赤霉醇和氯霉素等17种重要药物残留检测技术研究”第四完成人。农业部“中华农业科技奖”三等奖“主要肉蛋奶产品和蜂产品安全限量及控制标准研究”第八完成人。

代表性文章：

1. Shupeng Yang, Weimin Shi, Dingfei Hu, Suxia Zhang, Huiyan Zhang, Zhanhui Wang, Linli Cheng, Feifei Sun, Jianzhong Shen, Xingyuan Cao*. In vitro and In vivo Metabolite Profiling of Valnemulin Using Ultra-Performance Liquid Chromatography-Quadrupole/Time-of-Flight Hybrid Mass Spectrometry. Journal of Agricultural Food and Chemistry, 2014, 62, 9201-9210.

2. Yanshen Li, Xiangshu Luo, Shupeng Yang, Xingyuan Cao, Zhanhui Wang, Weimin Shi, Suxia Zhang.  High specific monoclonal production and developed an ELISA method for monitoring T-2 toxin in rice.  Journal of Agricultural Food and Chemistry, 2014, 62(7): 1492–1497

3. Xiaoqi Tao, Xuezhi Yu, Weimin Shi, Haiyang Jiang, Xia Wang, Zhanhui Wang, Lanlan Niu, Xiaoping Wu, Xi Xia, Jianzhong Shen. Development of a Rapid Chemiluminescent ciELISA for Simultaneous Determination of Florfenicol and Its metabolite Florfenicol Amine in Animal Meat Products. Journal of the Science of Food and Agriculture, 2014, 94(2): 301-307

4. Xiaoqi Tao, Haiyang Jiang, Jinghui Zhu, Xia Wang, Zhanhui Wang, Lanlan Niu, Xiaoping Wu, Weimin Shi, Jianzhong Shena*. An ultrasensitive chemiluminescent ELISA for determination of chloramphenicol in milk, milk powder, honey, eggs and chicken muscle. Food and Agricultural Immunology, 2014,  25(1): 137-148

5. Zhanhui Wang, Tiejun Mi, Huiyan Zhang, Yajie Sheng, Weimin Shi, Suxia Zhang, Jianzhong Shen. Hapten synthesis, monoclonal antibody production, and development of a competitive indirect enzyme-linked immunosorbnent assay for erythromycin in milk. Food Chemistry, 2015, 171, 98-107.