彭辰，男，中国农业大学动物医学院教授，博士生导师，获国家自然科学基金人才项目、国家十四五重点研发计划青年科学家项目资助。博士毕业于美国堪萨斯州立大学（Kansas State University）生物学系，主要研究痘病毒宿主特异性的分子机制,曾获堪萨斯州立大学博士生论坛一等奖，L.Evans博士杰出研究奖等。博士后供职于美国洛克斐勒大学(The Rockefeller University)以及美国国立卫生研究院(National Institutes of Health, NIH)，主要致力于研究牛痘病毒拮抗天然免疫反应的分子机制。2021年以“杰出人才”加入中国农业大学动物医学院全职工作。

任第十二届中国微生物学会兽医微生物专业委员会委员，中国饲料产业技术创新联盟常务理事，动物保健专委会委员，美国病毒学会（American Society of Virology）会员。任Frontiers in Cellular and Infection Microbiology编委（Member of the Editorial Board）,任PLoS Pathogens, Journal of Virology, Viruses 等杂志审稿人。

2016.6-2017.6 美国堪萨斯州立大学，博士后

2017.7-2018.1 美国洛克菲勒大学，博士后

2018.1-2020.12 美国国立卫生研究院（NIH）免疫与传染病研究所（NIAID）,博士后

主要研究方向包括牛痘、牛结节性皮肤病、羊痘病毒病原的复制机制以及免疫拮抗的分子机制；通过研发痘病毒抗病毒药物、疫苗、诊断试剂等，为牛痘、牛结节性皮肤病、猴痘等疫病的防控提供理论和技术支持；以改良牛痘病毒为载体研发针对各类传染病，如牛病毒性腹泻，新型冠状病毒肺炎等疫病的载体疫苗；开发靶向人或宠物癌症的新型溶瘤病毒治疗药物。

2021年获农业农村部“农业科研杰出人才”

2021年获北京市科技新星

兽医微生物实验

1.牛结节性皮肤病病毒复制机制的研究与抗病毒药物设计

国家“十四五”重点研发计划青年科学家专项，400万，在研，项目主持人

2.PLK1调控牛结节性皮肤病病毒复制的分子机制

国家自然科学基金面上项目，58万，在研，主持

3.牛结节性皮肤病病毒致病性与宿主嗜性机制的研究

国家级优秀人才项目，在研，主持

4.北京市科技新星计划

MVA靶向溶瘤病毒的研究，32万，在研，主持

# 通讯作者：

Xie, S., Cui, L., Liao, Z., Zhu, J., Ren, S., Niu, K., Li, H., Jiang, F., Wu, J., Wang, J., Wu, J., Song, B., Wu, W.^#, Peng, C^#. Genomic analysis of Asian variants of Lumpy Skin Disease Virus and an evaluation of its cellular tropism in vitro. NPJ Vaccines, 2024 (IF=9.3)

Xu, J., Liu, L., Zhi, F., Song, Y., Zhang, Z., Li, B., Zheng, F., Gao, P., Zhang, S., Zhang, Y., Zhang, Y., Qiu, Y., Jiang, B., Li, Y., Peng, C.^#, Chu, Y.# DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection. EMBO Reports,. 2024 (IF=9.4)

Wang, J., Zhu, J., Ren, S., Zhang, Z., Niu, K., Li, H., Wu, W.^#, Peng, C.^# The role of ferroptosis in virus infection. Frontiers in Microbiology, 2023 (IF=4.2)

Zhu, J., Gao, X., Li, Y., Zhang, Z., Xie, S., Ren, S., Li, Y., Li, H., Niu, K., Fu, S., Deng, Y., Li, Y., Moss, B., Wu, W.*, Peng, C.* Human Fam111A inhibits vaccinia virus replication by degrading viral protein I3 and is antagonized by poxvirus host range factor SPI-1. Proceedings of the National Academy of Sciences of USA, 2023 (IF=12.7)

Wang, P., Huang, S., Hao, C., Wang, Z., Wang, Z., Zhao, H., Liu, M., Tian, X., Ge, L., #Wu, W., #Peng, C., Establishment of a suspension MDBK cell line in serum-free medium for production of bovine alphaherpesvirus-1. Vaccines, 2021

Wang, Z., Liu, M., Zhao, H., Ma, W., Zhang, Y., #Wu, W., #Peng, C., Induction of robust and specific humoral and cellular immune responses by bovine viral diarrhea virus virus-like particles engineered with baculovirus expression system. Vaccines, 2021

Peng, C., and Moss B., Repair of a newly identified host range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells. Proceedings of the National Academy of Sciences of USA. 2019 (IF=12.7)

Peng, C., Wyatt, LS., Glushakow-Smith SG., Lal-Nag, M., Weisberg, AS., Moss, B., Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells. PLoS Pathogens. 2020 (IF=7.4)

Peng, C., Zhou, Y., Cao, S., Pant, A., Campos Guerrero ML., et al. Identification of vaccinia virus inhibitors and cellular functions necessary for efficient viral replication by screening bioactive and FDA-approved drugs. Vaccines, 2020 (IF=4.9)

Peng, C., Haller, S., Rahman, M., McFadden, G. and Rothenburg, S., Myxoma virus M156 is a specific inhibitor of rabbit PKR but contains a loss-of-function mutation in Australian virus isolates. Proceedings of the National Academy of Sciences of USA. 2016 (IF=12.7)

Yu,H., Peng, C., Zhang, C. et al.  Maladaptation after a virus host switch leads to increased activation of the pro-inflammatory NF-κB pathway,  Proceedings of the National Academy of Sciences of USA, 2022 (IF=12.7)

Park, C., Peng, C., Rahman, MJ., Haller, SL., Tazi, L., Brennan, G., Rothenburg, S., Orthopoxvirus K3 orthologs show virus- and host-specific inhibition of the antiviral protein kinase PKR. PLoS Pathogens. 2021