报告题目: Genome evolution and host specificity in Cryptosporidium
报告人: 肖立华 教授
报告地点: 动医动科大楼 401 室
报告时间: 4月11日(星期三)上午9: 00-10: 00
联系人: 索 勋 教授
报告人简介: 肖立华,美国疾病预防控制中心前研究员(资深科学家),2012年美国寄生虫学会杰出成就奖(Henry Baldwin Ward Medal)获得者。长期从事重要人兽共患寄生虫,如隐孢子虫、贾第虫、微孢子虫的分类、分子流行病学、环境生态学等研究,开展了许多基础性、原创性和系统性的研究,取得了一些在国际上有影响的独创性成果。目前致力于:
Investigates the molecular and genomic epidemiology of zoonotic parasites in humans and animals in the context of One Health.
Genotypes and subtypes waterborne and foodborne protozoan pathogens (Cryptosporidium, Giardia, Cyclospora, Microsporidia, Naegleria fowleri) in clinical and environmental samples.
Tracks sources and spread of protozoan parasites using advanced molecular detection tools.
Develops and manages CryptoNet–CDC's first molecular surveillance system for a parasite–a DNA sequence-based system for understanding U.S. transmission of cryptosporidiosis.
部分研究论文:
[1] Feng Y, Li N, Roellig DM, et al. Comparative genomic analysis of the IId subtype family of Cryptosporidium parvum [J]. Int J Parasitol, 2017, 47(5).
[2] Liu S, Roellig DM, Guo Y, et al. Evolution of mitosome metabolism and invasion-related proteins in Cryptosporidium [J]. BMC Genomics, 2016, 17(1): 1006.
[3] Liu S, Lin W, Zheng H, et al. Comparative genomics reveals Cyclospora cayetanensis possesses coccidia-like metabolism and invasion components but unique surface antigens [J]. BMC Genomics, 2016, 17(1): 316.
[4] Guo Y, Roellig DM, Li N, et al. Multilocus Sequence Typing Tool for Cyclospora cayetanensis [J]. Emerging Infectious Diseases, 2016, 22(8): 1464-1467.
[5] Guo Y, Tang K, Rowe LA, et al. Comparative genomic analysis reveals occurrence of genetic recombination in virulent Cryptosporidium hominis subtypes and telomeric gene duplications in Cryptosporidium parvum [J]. BMC Genomics, 2015, 16(1): 320.
[6] Karim MR, Zhang S, Jian F, et al. Multilocus typing of Cryptosporidium spp. and Giardia duodenalis from non-human primates in China [J]. Int J Parasitol, 2014, 44(13): 1039-1047.
[7] Wang Y, Yang W, Cama V, et al. Population genetics of Cryptosporidium meleagridis in humans and birds: evidence for cross-species transmission [J]. Int J Parasitol, 2014, 44(8): 515-521.
[8] Li N, Xiao L, Alderisio K, et al. Subtyping Cryptosporidium ubiquitum,a Zoonotic Pathogen Emerging in Humans [J]. Emerging Infectious Diseases, 2014, 20(2): 217-224.
[9] Feng Y, Torres E, Li N, et al. Population genetic characterisation of dominant Cryptosporidium parvum subtype IIaA15G2R1 [J]. Int J Parasitol, 2013, 43(14): 1141-1147.
[10] Na L, Xiao L, Cama VA, et al. Genetic Recombination and Cryptosporidium hominis Virulent Subtype IbA10G2 [J]. Emerging Infectious Diseases, 2013, 19(10): 1573-1582.
欢迎老师和同学参加!