科研经历：

孙洪磊，博士生导师，教授，畜牧兽医学会禽病学分会副秘书长。主要研究方向为：1）动物流感病毒流行生态及基因演化规律；2）动物流感病毒的公共卫生风险评估及跨种感染机制研究；3）新型动物流感疫苗研发。主持国家自然科学基金国际合作项目、面上项目、“十四五”国家重点研发计划等多项国家课题。以第一/通讯作者在Cell、The Lancet Microbe、PNAS、PLoS Pathogens、JVI等杂志发表SCI论文多篇。

主讲本科生课程《兽医传染病学》；

主讲研究生课程《畜禽疫病诊断案例分析》、《畜禽疫病诊断实验技术》。

1. 国家自然科学基金委员会，面上项目，32372996，HA蛋白稳定性在猪流感病毒跨宿主传播中的作用机制研究，2024-01-01 至 2027-12-31，50万元，在研，主持

2. 国家自然科学基金委员会，国际(地区)合作与交流项目，32161123001，EEID: U.S.-China:猪流感病毒基因演化及生态传播动力学研究，2022-01-01 至 2026-12-31，450万元，在研，主持

3. 科技部，国家重点研发计划-重点专项-地球系统与全球变化，2022YFF0802402-1，热点地区重大人兽共患病产生与传播的过程机制，2022-12 至 2027-11，90万元，在研，主持

4. 科技部，国家重点研发计划-重点专项-病原学与防疫技术体系研究，2023YFC2307501，大流行风险病毒的监测与识别， 2023-12 至 2026-11，204万元，在研，主持

1. Honglei Sun; Han Li; Qi Tong; Qiqi Han; Jiyu Liu; Haili Yu; Hao Song; Jianxun Qi; Jiaqi Li; Jizhe Yang; Riguo Lan; Guojing Deng; Haoyu Chang; Yajin Qu; Juan Pu; Yipeng Sun; Yu Lan; Dayan Wang; Yi Shi; William J. Liu; Kin-Chow Chang; George F. Gao; Jinhua Liu ; Airborne transmission of human-isolated avian H3N8 influenza virus between ferrets, Cell, 2023, 186(19): 4074-4084.

2. Han Li; Haoran Sun; Mengyan Tao; Qiqi Han; Haili Yu; Jiaqi Li; Xue Lu; Qi Tong; Juan Pu; Yipeng Sun; Litao Liu; Jinhua Liu; Honglei Sun*; Recombinant parainfluenza virus 5 expressing clade 2.3.4.4b H5 hemagglutinin protein confers broad protection against H5Ny influenza viruses, Journal of Virology, 2024, e01129-23.

3. Yang R#, Sun H#, Gao F#, Luo K#, Huang Z, Tong Q, Song H, Han Q, Liu J, Lan Y, Qi J, Li H, Chen S, Xu M, Qiu J, Zeng G, Zhang X, Huang C, Pei R, Zhan Z, Ye B, Guo Y, Zhou Y, Ye W, Yao D, Ren M, Li B, Yang J, Wang Y, Pu J, Sun Y, Shi Y, Liu WJ, Ou X, Gao GF, Gao L, Liu J. Human infection of avian influenza A H3N8 virus and the viral origins: a descriptive study. Lancet Microbe. 2022.

4. Honglei Sun, Guojing Deng, Haoran Sun, Jingwei Song, Wei Zhang, Han Li, Xiaohui Wei, Fangtao Li, Xin Zhang, Jiyu Liu, Juan Pu, Yipeng Sun, Qi Tong, Yuhai Bi, Yufeng Xie, Jianxun Qi, Kin-Chow Chang, George Fu Gao, Jinhua Liu, N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals, PNAS Nexus, 2022.

5. Fangtao Li, Jiyu Liu, Jizhe Yang, Haoran Sun, Zhimin Jiang, Chenxi Wang, Xin Zhang, Yinghui Yu, Chuankuo Zhao, Juan Pu, Yipeng Sun, Kin-Chow Chang, Jinhua Liu, Honglei Sun*. H9N2 virus-derived M1 protein promotes H5N6 virus release in mammalian cells: Mechanism of avian influenza virus inter-species infection in humans. PLoS Pathog. 2021, 17(12):e1010098.

6. Zhang Xuxiao#, Pu Juan, Sun Yipeng, Bi Yuhai, Jiang Zhimin, Xu Guanlong, Zhang Hongyu, Cao Jing, Chang Kin-Chow, Liu Jinhua*, Sun Honglei*. 2021. Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with FMRP in the murine brain. 2021, J Virol 95:e01272-20.

7. Honglei Sun#, Fangtao Li#, Qingzhi Liu , Jianyong Du, Litao Liu, Haoran Sun , Chong Li, Jiyu Liu, Xin Zhang , Jizhe Yang, Yuhong Duan, Yuhai Bi, Juan Pu, Yipeng Sun, Qi Tong, Yongqiang Wang, Xiangjun Du, Yuelong Shu, Kin-Chow Change and Jinhua Liu*, Mink is a highly susceptible host species to circulating human and avian influenza viruses, Emerging Microbes & Infections, 2021, VOL. 10.

8. Honglei Sun#, Juan Pu#, Yandi Wei#, Yipeng Sun, Jiao Hu, Litao Liu, Guanlong Xu, Weihua Gao, Chong Li, Xuxiao Zhang, Yinhua Huang, Kin-Chow Chang, Xiufan Liu, Jinhua Liu*, Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets, J Virol 90:6235–6243.

9. Jingwei Song#, Honglei Sun#, Yipeng Sun, Hsiang-Yu Yuan, Haoran Sun, Zhimin Jiang, Junda Zhu, Chenxi Wang, Weihua Gao, Tong Wang, Juan Pu, Yipeng Sun, Jinhua Liu*, Swine microRNAs ssc-miR-221-3p and ssc-miR-222 restrict the cross-species infection of avian influenza virus, Journal of Virology, 2020, 94(23): e01700-20.

10. Juan Pu#, Honglei Sun#, Yi Qu, Chenxi Wang, Weihua Gao, Junda Zhu, Yipeng Sun, Yuhai Bi, Yinhua Huang, Kin-Chow Chang, Jie Cui, Jinhua Liu, M gene reassortment in H9N2 influenza virus promotes early infection and replication: contribution to rising virus prevalence in chickens in China, 2017, J Virol 91: e02055-16.