个人简介：吴文学，中国农业大学动物医学院研究员、博士生导师。1994年毕业于原北京农业大学(兽医本科)，2002年获中国农业大学博士学位。1994年毕业留校工作至今，2013-2014在美国哈佛医学院做访问学者。现任教育部动物疫病快速诊断技术实验室负责人、国家奶牛产业技术体系奶牛场生物安全与综合防控岗位科学家、教育部新世纪优秀人才、中国兽药典委员会委员、农业部兽药评审专家、《中国兽医杂志》编委。先后主持或参加国家十三五重点研发专项、农业部公益性行业科研专项、国家科技支撑计划、教育部新世纪优秀人才支持计划、国家自然科学基金项目、农业部财政专项等40余项，获得国家发明专利8项、新兽药证书1个，发表论文60余篇(SCI论文20篇)，已指导硕士、博士研究生32名。

主要研究方向：畜禽传染病免疫调控机理研究、传染病诊断技术和疫苗研制。

目前主持课题：

[1]禽病高通量检测技术及配套试剂与设备研究，国家“十三五”重点研发专项，275万

[2]牛支原体抗体适体检测技术与试剂盒的研制，国家“十三五”重点研发专项，77万

[3]Cat L促进猪肺炎支原体感染后SIgA免疫应答的作用机制，国家自然基金，80万

[4]宠物疫病快速诊断与疫苗研究与示范，农业部公益性行业科研专项，75万

[5]国家奶牛产业技术体系，奶牛场生物安全与综合防控岗位

近年代表性文章：

[1]Jiang F, He J, Navarro-Alvarez N, Xu J, Li X, Li P, Wu W. Elongation Factor Tu and Heat Shock Protein 70 Are Membrane-Associated Proteins from Mycoplasma ovipneumoniae Capable of Inducing Strong Immune Response in Mice. PLoS One, Aug 18;11(8):e0161170, 2016

[2]Zhou Y, Wu W*, Lindholt JS, Sukhova GK, Libby P, Yu X, Shi GP .Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms. Cardiovasc Res,Jul 1;107(1):98-107,2015

[3]Zhang Y, Yu Z, Jiang F, Fu P, Shen J, Wu W*, Li J. Two DNA aptamers against avian influenza H9N2 virus prevent viral infection in cells. PLoS One,Mar 31;10(3): e0123060, 2015

[4]Jiahe Li, Jixiang Zhang, Ning Zhang, Yuewei Zhang, Wenxue Wu*, Jinxiang Li. Development of a replicative plasmid for gene expression in Mycoplasma bovis. Journal of Microbiological Methods, Jan,2015

[5]Jian Xu, Da Teng, Fei Jiang, Yuewei Zhang, Saeed A. El-Ashrom, Hui Wang, Zhenhong Sun, Jinyan He, Junjun Shen, Wenxue Wu*, Jinxiang Li. Mycoplasma gallisepticum MGA_0676 is a membrane-associated cytotoxic nuclease with a staphylococcal nuclease region essential for nuclear translocation and apoptosis induction in chicken cells, Appl Microbio Biotechnol, Feb,2015

[6]Zhang Y,Chen H,Zeng X, Wang P, Li J, Wu W*. Levamisole enhances immunity in ducklings vaccinated against Riemerella anatipestifer. Microbiol Immunol,Aug; 58(8):456-62,2014

[7]Wang J, Sjöberg S, Tang TT, Oörni K, Wu W, Liu C, Secco B, Tia V, Sukhova GK, Fernandes C, Lesner A, Kovanen PT, Libby P, Cheng X, Shi GP.Cathepsin G activity lowers plasma LDL and reduces atherosclerosis. Biochim Biophys Acta-Molecular Basis of Disease,Nov;1842(11):2174-83,2014

[8]Fu P,Sun ZH,Yu ZQ,Zhang YW,Shen JJ,Zhang HY,Xu W,Jiang F,Chen HL,Wu WX*. Enzyme Linked Aptamer Assay (ELAA),based on a competition format for rapid and sensitive detection of antibodies to Mycoplasma bovis in serum,Analytical Chemistry, 86(3):1701-1709, 2014

[9]Zhenhong Sun,Ping Fu,Kai Wei,Haiyan Zhang,Yuewei Zhang,Jian Xu,Fei Jiang,Xu Liu,Wei Xu,Wenxue Wu *. Identification of novel immunogenic proteins of Mycoplasma bovis and establishment of an indirect ELISA based on recombinant E1 beta subunit of the pyruvate dehydrogenase complex. PLoS One, 10;9(2):e88328,2014

[10]Yue-Wei Zhang,Hai-Yu Yan,Ping Fu,Fei Jiang,Yao Zhang,Wen-Xue Wu*,Jin-Xiang Li. Modified capillary electrophoresis based measurement of the binding between DNA aptamers and an unknown concentration target.Anal Bioanal Chem, 405(16):5549-55,2013

[11]Yin G, Qin M, Liu X, Suo J, Tang X, Tao G, Han Q, Suo X, Wu W*. An Eimeria vaccine candidate based on Eimeria tenella immune mapped protein 1 and the TLR-5 agonist Salmonella typhimurium FliC flagellin. Biochem Biophys Res Commun. Oct 25;440(3): 437-42,2013

[12]Jiahe Li,F. Chris Minion,Andrew C. Petersen,Fei Jiang,Sheng Yang,Panpan Guo, Jinxiang Li,Wenxue Wu*. Loop-mediated isothermal amplification for rapid and convenient detection of Mycoplasma hyopneumoniae,World J Microbiol Bioanal Chem, 29:607–616,2013

[13]Zhou M,Zhang G,Ren G,Gnanadurai CW,Li Z,Chai Q,Yang Y,Leyson CM, Wu W,Cui M,Fu ZF,Recombinant rabies viruses expressing GM-CSF or Flagellin are effective vaccines for both intramuscular and oral immunizations,PLoS One,8(5): e63384,2013