学术报告

 

主讲人：Dr. Fengyi Wan

 

中科院分子生物学博士，美国国立卫生研究员博士后，目前就职于约翰霍普金斯大学Bloomberg公共卫生学院微生物与免疫系Assistant Professor，在分子免疫学，生物化学，细胞生物学等领域具有深厚的研究背景。主要从事由细菌引起的肠道感染、炎症、肿瘤中的信号转导和基因调控方向的研究，在重要期刊上发表了多篇高水平文章。

 

Fu K, Sun X, Wier EM, Hodgson A, Liu Y, Sears CL, Wan F. (2016) Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-kB activation. Elife 5: e15018.

Hodgson A, Wier EM, Fu K, Sun X, Yu H, Zheng W, Sham HP, Johnson K, Bailey S, Vallance BA, Wan F (2015) Metalloprotease NleC suppresses host NF-kB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction. PLOS Pathog. 11: e1004705

Fu K, Sun X, Zheng W, Wier EM, Hodgson A, Tran DQ, Richard S, Wan F (2013) Sam68 modulates the promoter specificity of NF-kB and mediates expression of CD25 in activated T cells. Nat. Commun. 4: 1909

Wier EM, Neighoff J, Sun X, Fu K, Wan F (2012) Identification of an N-terminal truncation of the NF-kB p65 subunit that specifically modulates ribosomal protein S3-dependent NF-kB gene expression. J. Biol. Chem. 287: 43019-43029

Wan F, Weaver A, Gao X, Bern M, Hardwidge PR, Lenardo MJ (2011) IKKb phosphorylation regulates RPS3 nuclear translocation and NF-kB function during infection with Escherichia coli strain O157:H7. Nat. Immunol. 12: 335-343

 

 

报告题目：

 

Host-pathogen interactions in bacterially-driven colitis and colon tumorigenesis

 

时间：2016年11月23日（周三） 10:00

地点：实验动物楼报告厅

 

欢迎各位师生踊跃参加！

 

 

联系人：王少林、沈张奇；电话：62731686