张素霞，吉林省吉林市人，博士，教授，博士生导师。中国畜牧兽医学会兽医药理学与毒理学分会理事，中国农业大学动物医学院药理毒理教研组主任和农业部兽药安全监督检验测试中心（北京）副主任。主要从事动物性食品中兽药残留检测关键技术、生物样品前处理技术、兽药残留消除规律、兽药代谢产物鉴定等方面的研究。 近几年主持及参加科研项目10余项，主持国家自然科学基金面上项目“生物样品中磺胺类药物的荧光偏振免疫分析”，十五国家科技攻关重要技术标准专项子课题 “兽药残留检测及残留消除研究”，十一五国家科技支撑计划食品安全关键技术项目子课题“兽药残留的免疫亲和色谱净化技术研究”，国家863计划专题课题“莱克多巴胺等重要兽药残留快速免疫检测技术及产品研究”，国家973计划课题“受试化合物在畜禽体内的代谢研究”，国家标准和农业行业标准的制订项目等。 发表学术论文60余篇，其中SCI收录论文30余篇；参加申请国家发明专利12项，已获授权6项；研究制定国家和行业兽药残留检测方法标准32项，已发布国家标准21项，行业标准12项；已指导博士、硕士毕业生20余名；2009年获中华农业科技奖三等奖（第八完成人），2006年获国家科学技术进步二等奖（第九完成人），2005年获北京市科学技术一等奖（第四完成人），2001年获北京市科技进步二等奖（第四完成人）。 代表性文章： 1. Li, Y. S.; Liu, K. L.; Beier, R. C.; Cao, X. Y.; Shen, J. Z.; Zhang, S. X., Simultaneous determination of mequindox, quinocetone, and their major metabolites in chicken and pork by UPLC-MS/MS. Food chemistry 2014, 160, 171-179. 2. Li, Y.; Luo, X.; Yang, S.; Cao, X.; Wang, Z.; Shi, W.; Zhang, S., High specific monoclonal antibody production and development of an ELISA method for monitoring T-2 toxin in rice. Journal of agricultural and food chemistry 2014, 62, 1492-1497. 3. Mi, T. J.; Wang, Z. H.; Eremin, S. A.; Shen, J. Z.; Zhang, S. X., Simultaneous Determination of Multiple (Fluoro)quinolone Antibiotics in Food Samples by a One-Step Fluorescence Polarization Immunoassay. Journal of agricultural and food chemistry 2013, 61, 9347-9355. 4. Yang, S.; Li, Y.; Cao, X.; Hu, D.; Wang, Z.; Wang, Y.; Shen, J.; Zhang, S., Metabolic pathways of T-2 toxin in in vivo and in vitro systems of Wistar rats. Journal of agricultural and food chemistry 2013, 61, 9734-9743. 5. Liang, X.; Wang, Z.; Wang, C.; Wen, K.; Mi, T.; Zhang, J.; Zhang, S., A proof-of-concept receptor-based assay for sulfonamides. Analytical biochemistry 2013, 438, 110-116. 6. Li, Y. S.; Li, P.; Luo, X. S.; Hao, Z. H.; Wang, Z. H.; Shen, J. Z.; Cao, X. Y.; Zhang, S. X., Mixed immunoassay design for multiple chemical residues detection. Analytical and bioanalytical chemistry 2013, 405, 3307-3312. 7. Linli Cheng, Zhanhui Wang, Jianzhong Shen, Linxia Li, Haixia Wu, Suxia Zhang. A specific UPLC/ESI-MS/MS method for analysis of cyadox and its three main metabolites in fish samples. Analytical Methods, 2012, 4, 217-221. 8. Haixia Wu, Linxia Li, Jianzhong Shen, Ying Wang, Kaili Liu, Suxia Zhang. In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2012, 67-68: 175-85. 9. Yanshen Li, Zhanhui Wang, Ross C. Beier, Jianzhong Shen, David De Smet, Sarah De Saeger, and Suxia Zhang. T-2 Toxin, a Trichothecene Mycotoxin: Review of Toxicity, Metabolism, and Analytical Methods. Journal of Agricultural and Food Chemistry. 2011, 59, 3441-3453. 10. CongmingWu,Yan Li, Jianzhong Shen, Linli Cheng, Yanshen Li, Chunyan Yang, Peisheng Feng, Suxia Zhang. Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantification of Four Quinoxaline-1,4-dioxides in Swine Feed. Chromatographia 2009, 21（10）1605-1611. 11. Suxia Zhang, Zhongwei Liu, Xia Guo, Linli Cheng, Zhanhui Wang, Jianzhong Shen. Simultaneous determination and confirmation of chloramphenicol, thiamphenicol, florfenicol and florfenicol amine in chicken muscle by liquid chromatography–tandem mass spectrometry. Journal of Chromatography B, 2008, 875 (2): 399-404. 12. Suxia Zhang, Fengyun Sun, Jiancheng Li, Linli Cheng, Jianzhong Shen, Simultaneous determination of florfenicol and florfenicol amine in fish, shrimp and swine muscle by gas chromatography with a microcell electron capture detector. 2006, J AOAC Int., 89 (5), 1437-1442. |
