个人简介：

蒲娟，博士生导师，教授，获得国家自然科学基金优秀青年基金、入选教育部新世纪优秀人才支持计划、北京市高等学校青年英才计划、荣获北京市“青年教师教学基本功比赛”一等奖及最佳教案奖。以第一/通讯作者（含共同）在PNAS、JVI等杂志发表SCI论文多篇；以第一发明人获授权专利6项。主持国家自然科学基金面上项目、国际合作项目、优秀青年科学基金项目、国家科技支撑计划子课题、国家863计划子课题等国家和省部级课题项目。开展了广泛而良好的国内、国际间合作，与美国 WHO 流感生态参考实验室、美国俄克拉荷马大学地球观测与模拟研究中心、英国 Pirbright 研究所、英国诺丁汉大学等国外科研单位建立了长期合作关系。

工作经历：

2008-至今，中国农业大学动物医学院；2013.2-2013.5，School of Veterinary Medicine and Science， Nottingham University，UK；2013.11-2014.12, Infectious diseases Department of St. Jude Children’s Research Hospital，USA。

教学经历：

负责本科生课程《畜牧微生物学》,参与本科生课程《兽医传染病学大实验》、《兽医微生物学》；参与研究生课程《动物传染病专题》、《重要动物疫病防治实践》。

科研方向：

主要开展动物流感病毒流行病学与生态学及其机制研究，关注动物流感病毒的公共卫生学危害，追踪动物流感病毒在动物-环境-人中的流行与传播规律，揭示病毒致病及跨宿主传播作用机制，以探明流感病毒在生态圈中传播的关键要素，为科学防控动物和人间疫病提供理论依据。 

代表性文章：

1: Pu J#, Yin Y#, Liu J, Wang X, Zhou Y, Wang Z, Sun Y, Sun H, Li F, Song J, Qu R, Gao W, Wang D, Wang Z, Yan S, Chen M, Zeng J, Jiang Z, Sun H, Zong Y, Wang C, Tong Q, Bi Y, Huang Y, Du X, Chang KC, Liu J*. Reassortment with dominant chicken H9N2 influenza virus contributed to the fifth H7N9 virus human epidemic. J Virol. 2021 Mar 17:JVI.01578-20.

2: Song J, Wang C, Gao W, Sun H, Jiang Z, Wang K, Ren X, Wang Z, Tong Q, Wang M, Sun H, Sun Y, Liu J, Pu J*. A D200N hemagglutinin substitution contributes to antigenic changes and increased replication of avian H9N2 influenza virus. Vet Microbiol. 2020 Jun;245:108669.

3: Gao W, Zu Z, Liu J, Song J, Wang X, Wang C, Liu L, Tong Q, Wang M, Sun H, Sun Y, Liu J, Chang KC, Pu J*. Prevailing I292V PB2 mutation in avian influenza H9N2 virus increases viral polymerase function and attenuates IFN-β induction in human cells. J Gen Virol. 2019 Sep;100(9):1273-1281.

4: Wang C, Wang Z, Ren X, Wang L, Li C, Sun Y, Wang M, Tong Q, Sun H, Pu J*. Infection of chicken H9N2 influenza viruses in different species of domestic ducks. Vet Microbiol. 2019 Jun;233:1-4.

5: Li C, Wang S, Bing G, Carter RA, Wang Z, Wang J, Wang C, Wang L, Wu G, Webster RG, Wang Y, Sun H, Sun Y, Liu J, Pu J*. Genetic evolution of influenza H9N2 viruses isolated from various hosts in China from 1994 to 2013. Emerg Microbes Infect. 2017 Nov 29;6(11):e106.

6: Pu J#, Sun H#, Qu Y, Wang C, Gao W, Zhu J, Sun Y, Bi Y, Huang Y, Chang KC, Cui J, Liu J*. M Gene Reassortment in H9N2 Influenza Virus Promotes Early Infection and Replication: Contribution to Rising Virus Prevalence in Chickens in China. J Virol. 2017 Mar 29;91(8):e02055-16.

7: Xu G#, Zhang X#, Gao W, Wang C, Wang J, Sun H, Sun Y, Guo L, Zhang R, Chang KC, Liu J, Pu J*. Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity. J Virol. 2016 Aug 26;90(18):8105-14.

8: Wei Y, Xu G, Zhang G, Wen C, Anwar F, Wang S, Lemmon G, Wang J, Carter R, Wang M, Sun H, Sun Y, Zhao J, Wu G, Webster RG, Liu J, Pu J*. Antigenic evolution of H9N2 chicken influenza viruses isolated in China during 2009-2013 and selection of a candidate vaccine strain with broad cross-reactivity. Vet Microbiol. 2016;182:1-7.

9: Pu J#, Wang S#, Yin Y#, Zhang G, Carter RA, Wang J, Xu G, Sun H, Wang M, Wen C, Wei Y, Wang D, Zhu B, Lemmon G, Jiao Y, Duan S, Wang Q, Du Q, Sun M, Bao J, Sun Y, Zhao J, Zhang H, Wu G, Liu J*, Webster RG*. Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):548-53.